製品の概要

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris-saline. pH 7.3
  • Concentration information loading...
  • 特記事項(精製)Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab2751 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P
  • 追加情報Tested in peptide ELISA at 1:64000.
    IHC-P: Use at a concentration of 5 µg/ml.
    Western Blot: Preliminary experiments gave an approx 35kDa band in K562 lysates at 1µg/ml. However, this was accompanied by stronger bands at approx 45kDa and 48kDa. Please note that currently we cannot find an explanation in the literature for these extra bands given the predicted size of approx. 35kDda according to NP_057399.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能May function as an adapter protein. Required for efficient phagocytosis of apoptotic cells. Modulates cellular glycosphingolipid and cholesterol transport. May play a role in the internalization and endosomal trafficking of various LRP1 ligands, such as PSAP. Increases cellular levels of GTP-bound ARF6.
    • 組織特異性Widely expressed. Detected in macrophages, pancreas, kidney, skeletal muscle, heart, colon, intestine, lung, placenta and ovary.
    • 配列類似性Belongs to the ced-6 family.
      Contains 1 PID domain.
    • 細胞内局在Cytoplasm. May associate with the cytoplasmic side of the plasma membrane and early endosomes.
    • Information by UniProt
    • 参照データベース
    • 別名
      • CED6 antibody
      • Cell death protein 6 homolog antibody
      • Engulfment adapter protein antibody
      • Engulfment adaptor PTB domain containing 1 antibody
      • GULP antibody
      • GULP, engulfment adaptor PTB domain containing 1 antibody
      • GULP1 antibody
      • GULP1_HUMAN antibody
      • Protein GULP antibody
      • PTB domain adapter protein CED 6 antibody
      • PTB domain adapter protein CED-6 antibody
      • PTB domain adaptor protein CED6 antibody
      • PTB domain-containing engulfment adapter protein 1 antibody
      see all

    Anti-CED6 antibody 画像

    • ab2751 at 5ug/ml staining CED6 in human kidney tissue section by Immunohistochemistry (Formalin/PFA fixed paraffin-embedded sections). Tissue underwent antigen retrieval in steam with citrate buffer (pH 6.0). The AP-staining procedure was used for detection.

    Anti-CED6 antibody (ab2751) 使用論文

    ab2751 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab2751.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"