製品の概要

  • 製品名Anti-CEACAM7 antibody [BAC2]
    CEACAM7 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [BAC2] to CEACAM7
  • 特異性ab26281 recognizes exclusively CEACAM7 transiently expressed on the cell surface of transfected BOSC23 cells. It can be used to distinguish CEACAM7 from all other CEACAM and probably all pregnancy-specific glycoprotein molecules, namely CEACAM1 (BGP/CD66a), CEACAM3 (CGM1/CD66d), CEACAM4 (CGM7), CEACAM6 (NCA/CD66c), CEACAM7 (CGM2), CEACAM8 (CGM6/CD66b) and PSG1 (CD66f) based on its reactivity pattern with stable and transiently transfected mammalian cells expressing individual CEA family members.
  • アプリケーション適用あり: IHC-P, Flow Cyt, ELISA, IHC-Frmore details
  • 種交差性
    交差種: Human
  • 免疫原

    ab26281 was generated by immunisation of BALB/c mice with a CEACAM7/Fc fusion protein.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファーPreservative: 0.01% Sodium Azide
    Constituents: PBS, pH 7.2
  • Concentration information loading...
  • 精製度Protein G purified
  • ポリ/モノモノクローナル
  • クローン名BAC2
  • アイソタイプIgG1
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab26281 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P Use at an assay dependent concentration.
Flow Cyt Use at an assay dependent concentration. ab170190-Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
ELISA Use at an assay dependent concentration.
IHC-Fr Use at an assay dependent concentration.

ターゲット情報

  • 組織特異性Strongly down-regulated in colonic adenocarcinomas.
  • 配列類似性Belongs to the immunoglobulin superfamily. CEA family.
    Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
    Contains 1 Ig-like V-type (immunoglobulin-like) domain.
  • 細胞内局在Cell membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Carcinoembryonic antigen CGM 2 antibody
    • Carcinoembryonic antigen CGM2 antibody
    • Carcinoembryonic antigen gene family member 2 antibody
    • Carcinoembryonic antigen related cell adhesion molecule 7 antibody
    • Carcinoembryonic antigen-related cell adhesion molecule 7 antibody
    • CEA antibody
    • CEACAM 7 antibody
    • CEACAM7 antibody
    • CEAM7_HUMAN antibody
    • CGM 2 antibody
    • CGM2 antibody
    see all

Anti-CEACAM7 antibody [BAC2] 画像

  • Immunohistochemical analysis of gastric carcinoma tissue, stainin CEACAM7 with ab26281.

    Antigen retrieval was performed by heat mediation in a citrate buffer (pH 6). Sections were blocked with 10% normal goat serum in PBS for 30 minutes followed by incubation overnight at 4°C with the primary antibody (1/100 in 1% BSA). Staining was detected using DAB.

Anti-CEACAM7 antibody [BAC2] (ab26281) 使用論文

This product has been referenced in:
  • Kobayashi M  et al. Carcinoembryonic antigen-related cell adhesion molecules as surrogate markers for EGFR inhibitor sensitivity in human lung adenocarcinoma. Br J Cancer 107:1745-53 (2012). Read more (PubMed: 23099808) »
  • Zhou J  et al. Dynamic expression of CEACAM7 in precursor lesions of gastric carcinoma and its prognostic value in combination with CEA. World J Surg Oncol 9:172 (2011). IHC-P ; Human . Read more (PubMed: 22195770) »

See all 3 Publications for this product

Product Wall

Abcam guarantees this product to work in the species/application used in this Abreview.
Application Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Sample Human Tissue sections (normal tissue array - liver/lung/breast/kidney/col)
Specification normal tissue array - liver/lung/breast/kidney/col
Fixative Paraformaldehyde
Antigen retrieval step Heat mediated - Buffer/Enzyme Used: citrate
Permeabilization No
Blocking step Peroxidase block as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 100%
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投稿 Mar 27 2009

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"