製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to CEACAM3
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant protein fragment containing a sequence corresponding to a region within amino acids 55 and 241 of Human CEACAM3 (UniProt ID: P40198).

  • ポジティブ・コントロール
    • A431 whole cell lysate

法規制情報

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファー
    pH: 7.00
    Preservative: 0.01% Thimerosal (merthiolate)
    Constituents: 1.21% Tris, 0.75% Glycine, 20% Glycerol
  • Concentration information loading...
  • 精製度
    Immunogen affinity purified
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab111736 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/3000. Predicted molecular weight: 27 kDa.

ターゲット情報

  • 機能
    Major granulocyte receptor mediating recognition and efficient opsonin-independent phagocytosis of CEACAM-binding microorganisms, including Neissiria, Moxarella and Haemophilus species, thus playing an important role in the clearance of pathogens by the innate immune system. Responsible for RAC1 stimulation in the course of pathogen phagocytosis.
  • 組織特異性
    CGM1a, the predominant CGM1 transcript, is granulocyte-specific. Not detected out of the granulocytic lineage, such as monocytes, lymphocytes, spleen, testis, colon, brain, liver, pancreas, thymus, ovary, placenta, skeletal muscle, prostate, small intestine, heart, lung and kidney.
  • 配列類似性
    Belongs to the immunoglobulin superfamily. CEA family.
    Contains 1 Ig-like V-type (immunoglobulin-like) domain.
  • ドメイン
    The cytosolic domain is involved in S100A9 interaction.
  • 翻訳後修飾
    Tyrosine-phosphorylated in response to microbial binding. Tyr-230 and Tyr-241 are both required for phosphorylation to be detected.
  • 細胞内局在
    Membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • carcinoembryonic antibody
    • Carcinoembryonic antigen CGM1 antibody
    • Carcinoembryonic antigen gene family member 1 antibody
    • carcinoembryonic antigen related cell adhesion molecule 3 antibody
    • Carcinoembryonic antigen-related cell adhesion molecule 3 antibody
    • cd66 d antibody
    • CD66d antibody
    • CD66d antigen antibody
    • CEA antibody
    • CEACAM 3 antibody
    • CEACAM-3 antibody
    • Ceacam3 antibody
    • CEAM 3 antibody
    • CEAM-3 antibody
    • CEAM3 antibody
    • CEAM3_HUMAN antibody
    • CGM1 antibody
    • Nonspecific cross reacting antigen antibody
    • W264 antibody
    • W282 antibody
    see all

Anti-CEACAM3 antibody 画像

  • Anti-CEACAM3 antibody (ab111736) at 1/1000 dilution + A431 whole cell lysate at 30 µg

    Predicted band size : 27 kDa

プロトコール

Anti-CEACAM3 antibody (ab111736) 使用論文

ab111736 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab111736.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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