Anti-CDK1 (phospho Y15) 抗体 (ab69829)

製品の概要

• 製品名
  Anti-CDK1 (phospho Y15) antibody
  CDK1 一次抗体 製品一覧
• 製品の詳細
  Rabbit polyclonal to CDK1 (phospho Y15)
• アプリケーション
  適用あり: WBmore details
• 種交差性
  交差種: Human
  交差が予測される動物種: Mouse, Rat
• 免疫原

  Synthetic phospho-peptide derived from the C-terminus of human Cdc2

• ポジティブ･コントロール
  • HeLa Cell Lysate

製品の特性

• 製品の状態
  Liquid
• 保存方法
  Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
• バッファー
  Preservative: 0.09% Sodium Azide
  Constituents: 50% Glycerol, PBS, pH 7.2
• Concentration information loading...
• 精製度
  Immunogen affinity purified
• ポリ/モノ
  ポリクローナル
• アイソタイプ
  IgG
• 研究分野
  • Cell Biology
  • Cell Cycle
  • Kinases/Phosphatases
  • Cdks

  • Neuroscience
  • Neurology process
  • Neural Signal Transduction

  • Neuroscience
  • Neurology process
  • Neurodegenerative disease
  • Other

  • Epigenetics and Nuclear Signaling
  • Cell cycle
  • Kinases/Phosphatases
  • Cdks

関連製品

• Compatible Secondaries
  • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
  • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)
• Positive Controls
  • HeLa nuclear extract lysate (ab14655)

アプリケーション

ターゲット情報

• 機能
  Plays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis. p34 is a component of the kinase complex that phosphorylates the repetitive C-terminus of RNA polymerase II.
• 組織特異性
  Isoform 2 is found in breast cancer tissues.
• 配列類似性
  Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
  Contains 1 protein kinase domain.
• 細胞内局在
  Nucleus.

• Target information above from: UniProt accession P06493 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• 参照データベース
  • Entrez Gene: 983 Human
  • Entrez Gene: 12534 Mouse
  • Entrez Gene: 54237 Rat
  • Omim: 116940 Human
  • SwissProt: P06493 Human
  • SwissProt: P11440 Mouse
  • SwissProt: P39951 Rat
  • Unigene: 334562 Human

  • Unigene: 281367 Mouse
  • Unigene: 6934 Rat

  see all
• 製品の状態
  CDK1 can be located to the Nucleus, cytoplasm and Mithocondria. It's cytoplasmic during interphase and reversibly translocated from cytoplasm to the nucleus when phosphorilated before G2-M transition when associated with cyclin-B1. Accumulates in mitochondria in G2-arrested cells upon DNA-damage.
• 別名
  • Cdc 2 antibody
  • Cdc2 antibody
  • CDC28A antibody

  • CDK 1 antibody
  • CDK1 antibody
  • CDK1_HUMAN antibody
  • CDKN1 antibody
  • CELL CYCLE CONTROLLER CDC2 antibody
  • Cell division control protein 2 antibody
  • Cell division control protein 2 homolog antibody
  • Cell division cycle 2 G1 to S and G2 to M antibody
  • Cell division protein kinase 1 antibody
  • Cell Divsion Cycle 2 Protein antibody
  • Cyclin Dependent Kinase 1 antibody
  • Cyclin-dependent kinase 1 antibody
  • DKFZp686L20222 antibody
  • MGC111195 antibody
  • p34 Cdk1 antibody
  • p34 protein kinase antibody
  • P34CDC2 antibody

  see all

プロトコール

• Western blot protocols