Anti-Cdc6 抗体 (ab125195)
Key features and details
- Rabbit polyclonal to Cdc6
- Suitable for: IHC-P
- Reacts with: Mouse, Human
- Isotype: IgG
製品の概要
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製品名
Anti-Cdc6 antibody
Cdc6 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to Cdc6 -
由来種
Rabbit -
アプリケーション
適用あり: IHC-Pmore details -
種交差性
交差種: Mouse, Human
交差が予測される動物種: Chimpanzee, Gorilla -
免疫原
Synthetic peptide, corresponding to a region within N terminal amino acids 1-50 of Human Cdc6 (NP_001245.1).
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ポジティブ・コントロール
- Human Breast Carcinoma, Colon Carcinoma, Non-Small Cell Lung Cancer, Ovarian Carcinoma and Prostate Carcinoma tissues; Mouse Colon Carcinoma CT26, Renal Cell Carcinoma and Teratoma tissues.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
pH: 6.8
Preservative: 0.09% Sodium azide
Constituents: 99% Tris buffered saline, 0.1% BSA -
Concentration information loading...
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精製度
Immunogen affinity purified -
特記事項(精製)
ab125195 was affinity purified using an epitope specific to Cdc6 immobilized on a solid support. -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab125195の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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IHC-P |
1/100 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. Likely to work with frozen sections
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特記事項 |
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IHC-P
1/100 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. Likely to work with frozen sections |
ターゲット情報
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機能
Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated. -
配列類似性
Belongs to the CDC6/cdc18 family. -
細胞内局在
Nucleus. Cytoplasm. The protein is nuclear in G1 and cytoplasmic in S-phase cells. - Information by UniProt
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参照データベース
- Entrez Gene: 990 Human
- Entrez Gene: 23834 Mouse
- Omim: 602627 Human
- SwissProt: Q99741 Human
- SwissProt: O89033 Mouse
- Unigene: 405958 Human
- Unigene: 20912 Mouse
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別名
- Cdc 18L antibody
- Cdc 6 antibody
- CDC18 (cell division cycle 18, S.pombe, homolog) like antibody
see all
画像
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ab125195 at 1/100 dilution staining Cdc6 in Formalin-Fixed, Paraffin-Embedded Human colon carcinoma tissue by Immunohistochemistry.
Detection: DAB staining. -
ab125195 at 1/100 dilution staining Cdc6 in Formalin-Fixed, Paraffin-Embedded Mouse teratoma tissue by Immunohistochemistry.
Detection: DAB staining.
データシートおよび資料
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Datasheet download
参考文献 (1)
ab125195 は 1 報の論文で使用されています。
- Wang X et al. Targeting RNA helicase DHX33 blocks Ras-driven lung tumorigenesis in vivo. Cancer Sci 111:3564-3575 (2020). PubMed: 32767810