製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to CDC42EP2
  • 特異性
    ab92673 detects endogenous levels of total CDC42EP2 protein.
  • アプリケーション
    適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat
  • 免疫原

    Synthetic peptide derived from the internal region of Human CDC42EP2.

  • ポジティブ・コントロール
    • Extracts from K562 cells

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab92673 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
ELISA
  • 追加情報
    ELISA: 1/40000.
    WB: 1/500 - 1/1000. Predicted molecular weight: 22 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能
      Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation in fibroblasts in a CDC42-dependent manner.
    • 組織特異性
      Highly expressed in the heart. Weakly expressed in the pancreas and liver.
    • 配列類似性
      Belongs to the BORG/CEP family.
      Contains 1 CRIB domain.
    • ドメイン
      The CRIB domain mediates interaction with CDC42.
    • 細胞内局在
      Endomembrane system. Cytoplasm > cytoskeleton.
    • Information by UniProt
    • 参照データベース
    • 別名
      • Binder of Rho GTPases 1 antibody
      • BORG1 antibody
      • BORG1_HUMAN antibody
      • CDC42 effector protein (Rho GTPase binding) 2 antibody
      • Cdc42 effector protein 2 antibody
      • Cdc42ep2 antibody
      • CEP2 antibody
      • CRIB-containing BOGR1 protein antibody
      see all

    画像

    • All lanes : Anti-CDC42EP2 antibody (ab92673) at 1/500 dilution

      Lane 1 : Extract from K562 cells
      Lane 2 : Extract from K562 cells with blocking peptide at 10 µg

      Lysates/proteins at 30 µg per lane.


      Predicted band size : 22 kDa

    プロトコール

    参考文献

    ab92673 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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