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RabMAb

Anti-Cdc37 抗体 [EPR4934] (ab109419)

製品の概要

  • 製品名
    Anti-Cdc37 antibody [EPR4934]
    Cdc37 一次抗体 製品一覧
  • 製品の詳細
    Rabbit monoclonal [EPR4934] to Cdc37
  • アプリケーション
    適用あり: WB, IP, IHC-P, Flow Cytmore details
    適用なし: ICC
  • 種交差性
    交差種: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide corresponding to residues in Human Cdc37.

  • ポジティブ・コントロール
    • Jurkat, A431, K562, LnCaP and SW480 cell lysates; Human breast ductal infiltrating carcinoma
  • 特記事項

    This product is a recombinant rabbit monoclonal antibody.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab109419 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/1000 - 1/10000. Detects a band of approximately 50 kDa (predicted molecular weight: 44 kDa).
IP 1/10 - 1/100.
IHC-P 1/250 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
Flow Cyt 1/10 - 1/100. ab172730-Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.
  • 追加情報
    Is unsuitable for ICC.
  • ターゲット情報

    • 機能
      Co-chaperone that binds to numerous kinases and promotes their interaction with the Hsp90 complex, resulting in stabilization and promotion of their activity.
    • 配列類似性
      Belongs to the CDC37 family.
    • 翻訳後修飾
      Constitutively sumoylated by UBE2I.
    • 細胞内局在
      Cytoplasm.
    • Information by UniProt
    • 参照データベース
    • 別名
      • CDC 37 antibody
      • Cdc37 antibody
      • CDC37 cell division cycle 37 homolog antibody
      • CDC37 cell division cycle 37 S cerevisiae homolog antibody
      • CDC37 cell division cycle 37, S cerevisiae, homolog of antibody
      • Cdc37 homolog antibody
      • CDC37 protein antibody
      • CDC37_HUMAN antibody
      • CDC37A antibody
      • cell division cycle 37 antibody
      • Cell division cycle 37 homolog antibody
      • Hsp90 chaperone protein kinase targeting subunit antibody
      • Hsp90 chaperone protein kinase targeting subunit p50Cdc37 antibody
      • Hsp90 chaperone protein kinase-targeting subunit antibody
      • Hsp90 co chaperone Cdc37 antibody
      • Hsp90 co-chaperone Cdc37 antibody
      • p50 antibody
      • p50Cdc37 antibody
      • S cerevisiae hypothetical protein CDC37 antibody
      see all

    画像

    • All lanes : Anti-Cdc37 antibody [EPR4934] (ab109419) at 1/1000 dilution

      Lane 1 : Jurkat cell lysate
      Lane 2 : A431 cell lysate
      Lane 3 : K562 cell lysate
      Lane 4 : LnCaP cell lysate
      Lane 5 : SW480 cell lysate

      Lysates/proteins at 10 µg per lane.


      Predicted band size : 44 kDa
    • ab109419, at 1/250 dilution, staining Cdc37 in Human breast ductal infiltrating carcinoma by Immunohistochemistry.

    参考文献

    This product has been referenced in:
    • Synoradzki K & Bieganowski P Middle domain of human Hsp90 isoforms differentially binds Aha1 in human cells and alters Hsp90 activity in yeast. Biochim Biophys Acta 1853:445-52 (2015). Read more (PubMed: 25486457) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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