製品の概要

  • 製品名Anti-Cdc25C antibody
    Cdc25C 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Cdc25C
  • アプリケーション適用あり: IHC-Pmore details
  • 種交差性
    交差種: Mouse, Human
    交差が予測される動物種: Chimpanzee, Gorilla, Orangutan
  • 免疫原

    Synthetic peptide corresponding to a region between residue 150 and 200 of human Cdc25C (NP_001781.2)

  • ポジティブ・コントロール
    • human seminoma, human breast carcinoma, mouse teratoma.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab84485 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P 1/100 - 1/500.

ターゲット情報

  • 機能Functions as a dosage-dependent inducer in mitotic control. It is a tyrosine protein phosphatase required for progression of the cell cycle. It directly dephosphorylates CDK1 and activate its kinase activity.
  • 配列類似性Belongs to the MPI phosphatase family.
    Contains 1 rhodanese domain.
  • 発生段階Expressed predominantly in G2 phase.
  • 翻訳後修飾Phosphorylated by CHK1 on Ser-216. This phosphorylation creates a binding site for 14-3-3 protein and inhibits the phosphatase. Phosphorylated by PLK4.
  • 細胞内局在Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CDC 25 antibody
    • Cdc 25C antibody
    • CDC25 antibody
    • CDC25C antibody
    • Cell division cycle 25 homolog C antibody
    • Cell division cycle 25C antibody
    • Cell division cycle 25C protein antibody
    • Dual specificity phosphatase Cdc25C antibody
    • M phase inducer phosphatase 3 antibody
    • M-phase inducer phosphatase 3 antibody
    • Mitosis inducer CDC25 antibody
    • MPIP3 antibody
    • MPIP3_HUMAN antibody
    • Phosphotyrosine phosphatase antibody
    • PPP1R60 antibody
    • protein phosphatase 1, regulatory subunit 60 antibody
    see all

Anti-Cdc25C antibody 画像

  • ab84485 at a dilution of 1/250 staining a formalin-fixed, paraffin-embedded section of human seminoma.
    Detection: DAB staining.
  • ab84485 at a dilution of 1/250 staining a formalin-fixed, paraffin-embedded section of human breast carcinoma.
    Detection: DAB staining.
  • ab84485 at a dilution of 1/250 staining formalin-fixed, paraffin-embedded section of mouse teratoma.
    Detection: DAB staining.

Anti-Cdc25C antibody (ab84485) 使用論文

This product has been referenced in:
  • Shirazi Fard S  et al. Heterogenic final cell cycle by chicken retinal Lim1 horizontal progenitor cells leads to heteroploid cells with a remaining replicated genome. PLoS One 8:e59133 (2013). IHC-P . Read more (PubMed: 23527113) »

See 1 Publication for this product

Product Wall

There are currently no Abreviews or Questions for ab84485.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"