製品の概要

  • 製品名Anti-Cdc14B antibody
    Cdc14B 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Cdc14B
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Full length Human Cdc14B (ENSP00000265659, amino acids 1-471).

  • ポジティブ・コントロール
    • Human liver tissue lysate; Cdc14B transfected 293T cell lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab104415 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: Isoform 2, 57 ; Isoform 3, 54 kDa.

ターゲット情報

  • 機能Dual-specificity phosphatase involved in DNA damage response. Essential regulator of the G2 DNA damage checkpoint: following DNA damage, translocates to the nucleus and dephosphorylates FZR1/CDH1, a key activator of the anaphase promoting complex/cyclosome (APC/C). Dephosphorylation of FZR1/CDH1 activates the APC/C, leading to the ubiquitination of PLK1, preventing entry into mitosis. Preferentially dephosphorylates proteins modified by proline-directed kinases.
  • 配列類似性Belongs to the protein-tyrosine phosphatase family. Non-receptor class CDC14 subfamily.
  • ドメインComposed of two structurally equivalent A and B domains that adopt a dual specificity protein phosphatase (DSP) fold.
  • 細胞内局在Nucleus > nucleolus. Nucleus > nucleoplasm. Following DNA damage, translocates from the nucleolus to the nucleoplasm and interacts with FZR1/CDH1.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CC14B_HUMAN antibody
    • Cdc 14B antibody
    • Cdc 14B1 antibody
    • Cdc 14B2 antibody
    • CDC 14B3 antibody
    • CDC14 cell division cycle 14 homolog B antibody
    • CDC14 homolog B antibody
    • Cdc14b antibody
    • Cdc14B1 antibody
    • Cdc14B2 antibody
    • CDC14B3 antibody
    • Cell division cycle 14 homolog B antibody
    • Dual specificity protein phosphatase CDC14B antibody
    • hCDC 14B antibody
    • hCDC14B antibody
    • OTTHUMP00000063774 antibody
    see all

Anti-Cdc14B antibody 画像

  • Anti-Cdc14B antibody (ab104415) at 1 µg/ml + Human liver tissue lysate at 50 µg

    Predicted band size : Isoform 2, 57 ; Isoform 3, 54 kDa
  • All lanes : Anti-Cdc14B antibody (ab104415) at 1 µg/ml

    Lane 1 : Cdc14B transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.


    Predicted band size : Isoform 2, 57 ; Isoform 3, 54 kDa

Anti-Cdc14B antibody (ab104415) 使用論文

ab104415 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab104415.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"