製品の概要

  • 製品名Anti-CD97 antibody
    CD97 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to CD97
  • 特異性Immunogen is 100% homologous in human isoforms a, b, c and d.
  • アプリケーション適用あり: WB, IHC-Pmore details
  • 種交差性
    交差種: Human, Chimpanzee
    交差が予測される動物種: Monkey
  • 免疫原

    A portion of amino acids 220-270 of human CD97

  • ポジティブ・コントロール
    • K562 cell lysate; human spleen tissue

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab72107 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 - 3 µg/ml. Detects a band of approximately 92 kDa (predicted molecular weight: 92 kDa).
IHC-P Use a concentration of 10 µg/ml.

ターゲット情報

  • 機能Receptor potentially involved in both adhesion and signaling processes early after leukocyte activation. Plays an essential role in leukocyte migration.
  • 組織特異性Broadly expressed, found on most hematopoietic cells, including activated lymphocytes, monocytes, macrophages, dendritic cells, and granulocytes. Expressed also abundantly by smooth muscle cells. Expressed in thyroid, colorectal, gastric, esophageal and pancreatic carcinomas too. Expression are increased under inflammatory conditions in the CNS of multiple sclerosis and in synovial tissue of patients with rheumatoid arthritis. Increased expression of CD97 in the synovium is accompagnied by detectable levels of soluble CD97 in the synovial fluid.
  • 配列類似性Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
    Contains 5 EGF-like domains.
    Contains 1 GPS domain.
  • ドメインThe first two EGF domains mediate the interaction with DAF. A third tandemly arranged EGF domain is necessary for the structural integrity of the binding region.
    Binding to chondroitin sulfate is mediated by the fourth EGF domain.
  • 翻訳後修飾Proteolytically cleaved into 2 subunits, an extracellular alpha subunit and a seven-transmembrane subunit.
  • 細胞内局在Cell membrane and Secreted > extracellular space.
  • Information by UniProt
  • 参照データベース
  • 別名
    • ADGRE5 antibody
    • Adhesion G protein-coupled receptor E5 antibody
    • CD 97 antibody
    • CD_antigen=CD97 antibody
    • CD97 antibody
    • CD97 antigen antibody
    • CD97 antigen subunit beta antibody
    • CD97 molecule antibody
    • CD97_HUMAN antibody
    • Leukocyte antigen CD97 antibody
    • Seven span transmembrane protein antibody
    • Seven transmembrane helix receptor antibody
    • Seven transmembrane heterodimeric receptor associated with inflammation antibody
    • TM7LN 1 antibody
    • TM7LN1 antibody
    see all

Anti-CD97 antibody 画像

  • All lanes : Anti-CD97 antibody (ab72107) at 2 µg/ml

    Lane 1 : K562 cell lysate
    Lane 2 : K562 cell lysate with immunizing peptide


    Predicted band size : 92 kDa
    Observed band size : 75 kDa (why is the actual band size different from the predicted?)
  • Analysis of CD97 expression in human spleen tissue using ab72107 at 10ug/ml.

Anti-CD97 antibody (ab72107) 使用論文

ab72107 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"