PE Anti-CD90 / Thy1 抗体 [G7] (ab24904)
Key features and details
- PE Rat monoclonal [G7] to CD90 / Thy1
- Suitable for: Flow Cyt
- Reacts with: Mouse
- Conjugation: PE. Ex: 488nm, Em: 575nm
- Isotype: IgG2c
製品の概要
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製品名
PE Anti-CD90 / Thy1 antibody [G7]
CD90 / Thy1 一次抗体 製品一覧 -
製品の詳細
PE Rat monoclonal [G7] to CD90 / Thy1 -
由来種
Rat -
標識
PE. Ex: 488nm, Em: 575nm -
特異性
ab24904 is specific for Thy 1.1 and Thy 1.2 alloantigens (Thy 1 epitope region A). -
アプリケーション
適用あり: Flow Cytmore details -
種交差性
交差種: Mouse -
免疫原
Tissue, cells or virus corresponding to Mouse CD90/ Thy1. Mouse T cell hybridoma C6/G8
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エピトープ
Thy 1 epitope region A -
特記事項
ab24904 stimulates T-cell proliferation and IL2 secretion, via signalling through the T-cell receptor/CD3 complex. ab24904 has also been reported to promote apoptosis of thymocytes and CTL clones and to mediate adhesion of thymocytes to thymic stroma.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C. Store In the Dark. -
バッファー
pH: 7.3
Preservative: 0.09% Sodium azide
Constituents: PBS, 16% Sucrose
Stabilising agent. -
Concentration information loading...
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精製度
Affinity purified -
一次抗体 備考
ab24904 stimulates T-cell proliferation and IL2 secretion, via signalling through the T-cell receptor/CD3 complex. ab24904 has also been reported to promote apoptosis of thymocytes and CTL clones and to mediate adhesion of thymocytes to thymic stroma. -
ポリ/モノ
モノクローナル -
クローン名
G7 -
アイソタイプ
IgG2c -
軽鎖の種類
kappa -
研究分野
関連製品
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Alternative Versions
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab24904の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
Flow Cyt | (1) |
Use 2µg for 106 cells.
ab154450 - Rat monoclonal IgG2c, is suitable for use as an isotype control with this antibody. |
特記事項 |
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Flow Cyt
Use 2µg for 106 cells. ab154450 - Rat monoclonal IgG2c, is suitable for use as an isotype control with this antibody. |
ターゲット情報
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機能
May play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain. -
配列類似性
Contains 1 Ig-like V-type (immunoglobulin-like) domain. -
細胞内局在
Cell membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 21838 Mouse
- SwissProt: P01831 Mouse
- Unigene: 3951 Mouse
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別名
- CD7 antibody
- CD90 antibody
- CD90 antigen antibody
see all
画像
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (8)
ab24904 は 8 報の論文で使用されています。
- Wan YM et al. Mesenchymal stem cells reduce alcoholic hepatitis in mice via suppression of hepatic neutrophil and macrophage infiltration, and of oxidative stress. PLoS One 15:e0228889 (2020). PubMed: 32045450
- Smith AJ et al. Isolation and characterization of resident endogenous c-Kit+ cardiac stem cells from the adult mouse and rat heart. Nat Protoc 9:1662-81 (2014). PubMed: 24945383
- Tingling JD et al. CD24 expression identifies teratogen-sensitive fetal neural stem cell subpopulations: evidence from developmental ethanol exposure and orthotopic cell transfer models. PLoS One 8:e69560 (2013). Flow Cyt ; Mouse . PubMed: 23894503
- Hueber AO et al. Thy-1 triggers mouse thymocyte apoptosis through a bcl-2-resistant mechanism. J Exp Med 179:785-96 (1994). PubMed: 7906706
- Ucker DS et al. Activation-driven T cell death. II. Quantitative differences alone distinguish stimuli triggering nontransformed T cell proliferation or death. J Immunol 149:1583-92 (1992). PubMed: 1380534
- He HT et al. Thy-1 supports adhesion of mouse thymocytes to thymic epithelial cells through a Ca2(+)-independent mechanism. J Exp Med 173:515-8 (1991). PubMed: 1671083
- Tentori L et al. Proliferation and production of IL-2 and B cell stimulatory factor 1/IL-4 in early fetal thymocytes by activation through Thy-1 and CD3. J Immunol 140:1089-94 (1988). PubMed: 2893823
- Gunter KC et al. T cell-activating properties of an anti-Thy-1 monoclonal antibody. Possible analogy to OKT3/Leu-4. J Exp Med 159:716-30 (1984). PubMed: 6142077