Anti-CD89 抗体 [MIP7c] (ab53357)
Key features and details
- Mouse monoclonal [MIP7c] to CD89
- Suitable for: Inhibition Assay
- Reacts with: Human
- Isotype: IgG1
製品の概要
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製品名
Anti-CD89 antibody [MIP7c]
CD89 一次抗体 製品一覧 -
製品の詳細
Mouse monoclonal [MIP7c] to CD89 -
由来種
Mouse -
特異性
ab53357 recognises the EC1 domain of the CD89 extracellular region. -
アプリケーション
適用あり: Inhibition Assaymore details -
種交差性
交差種: Human -
免疫原
Soluble CD89
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at 4°C (stable for up to 12 months). Store at -20°C or -80°C. -
バッファー
Preservative: 0.1% Sodium azide
Constituent: PBS -
Concentration information loading...
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精製度
Protein A purified -
ポリ/モノ
モノクローナル -
クローン名
MIP7c -
アイソタイプ
IgG1 -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab53357の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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Inhibition Assay |
特記事項 |
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Inhib: Use 4µg for 105 cells.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
ターゲット情報
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機能
Binds to the Fc region of immunoglobulins alpha. Mediates several functions including cytokine production. -
組織特異性
Isoform A.1, isoform A.2 and isoform A.3 are differentially expressed between blood and mucosal myeloid cells. Isoform A.1, isoform A.2 and isoform A.3 are expressed in monocytes. Isoform A.1 and isoform A.2 are expressed in alveolar macrophages; however only one isoform is expressed at alveolar macrophages surfaces. -
配列類似性
Contains 2 Ig-like C2-type (immunoglobulin-like) domains. -
細胞内局在
Secreted and Cell membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 2204 Human
- Omim: 147045 Human
- SwissProt: P24071 Human
- Unigene: 659872 Human
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別名
- CD89 antibody
- Fc alpha receptor antibody
- Fc fragment of IgA, receptor for antibody
see all
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (1)
ab53357 は 1 報の論文で使用されています。
- Duchemin M et al. IgA Targeting Human Immunodeficiency Virus-1 Envelope gp41 Triggers Antibody-Dependent Cellular Cytotoxicity Cross-Clade and Cooperates with gp41-Specific IgG to Increase Cell Lysis. Front Immunol 9:244 (2018). PubMed: 29651286