製品の概要

  • 製品名
    Anti-CD86 antibody [B-T7]
    CD86 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [B-T7] to CD86
  • 由来種
    Mouse
  • アプリケーション
    適用あり: Functional Studies, Flow Cytmore details
  • 種交差性
    交差種: Human
  • 免疫原

    B70 transfected P815 cell line

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab47170 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Functional Studies
Flow Cyt
  • 追加情報
    Flow Cyt: Use 10µl for 106 cells.
    FuncS: Use at an assay dependent dilution. Inhibits Mixed Lymphocyte Culture


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.

    • ターゲット情報

    • 機能
      Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. Isoform 2 interferes with the formation of CD86 clusters, and thus acts as a negative regulator of T-cell activation.
    • 組織特異性
      Expressed by activated B-lymphocytes and monocytes.
    • 配列類似性
      Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
      Contains 1 Ig-like V-type (immunoglobulin-like) domain.
    • 翻訳後修飾
      Polyubiquitinated; which is promoted by MARCH8 and results in endocytosis and lysosomal degradation.
    • 細胞内局在
      Membrane.
    • Information by UniProt
    • 参照データベース
      • 別名
        • Activation B7-2 antigen 3 antibody
        • Activation B7-2 antigen antibody
        • B-lymphocyte activation antigen B7-2 2 antibody
        • B-lymphocyte activation antigen B7-2 antibody
        • B7 2 antibody
        • B7 antibody
        • B7-2 antibody
        • B7.2 antibody
        • B70 antibody
        • B72 antigen antibody
        • BU63 antibody
        • CD28 antigen ligand 2 2 antibody
        • CD28 antigen ligand 2 antibody
        • Cd28l2 antibody
        • CD28LG2 antibody
        • CD86 antibody
        • CD86 antigen (CD28 antigen ligand 2, B7-2 antigen) 1, 2 antibody
        • CD86 antigen (CD28 antigen ligand 2, B7-2 antigen) antibody
        • CD86 antigen antibody
        • CD86 molecule antibody
        • CD86_HUMAN antibody
        • CLS1 antibody
        • CTLA-4 counter-receptor B7.2 2, 3 antibody
        • CTLA-4 counter-receptor B7.2 antibody
        • Early T-cell costimulatory molecule 1 antibody
        • ETC-1 antibody
        • FUN 1 antibody
        • FUN-1 antibody
        • LAB72 antibody
        • Ly-58 antibody
        • Ly58 antibody
        • MB7 antibody
        • MB7-2 antibody
        • Membrane glycoprotein antibody
        • MGC34413 antibody
        • T-lymphocyte activation antigen CD86 antibody
        • TS/A-2 antibody
        see all

      画像

      • Flow Cytometry - Anti-CD86 antibody [B-T7] (ab47170)
        Flow Cytometry - Anti-CD86 antibody [B-T7] (ab47170)
        A typical staining pattern with ab47170 monoclonal antibody of monocytes

      プロトコール

      参考文献

      ab47170 has not yet been referenced specifically in any publications.

      ab47170 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

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      Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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