製品の概要

  • 製品名
    Anti-CD80 antibody [2A2]
    CD80 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [2A2] to CD80
  • アプリケーション
    適用あり: IHC-P, WB, ELISA, ICC/IFmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Purified recombinant fragment of Human CD80 expressed in E. coli spanning amino acids 35-141.

  • ポジティブ・コントロール
    • BCBL-1 cells
  • 特記事項

    This product was changed from ascites to supernatant. Lot no’s high than GR160888-29 are from Tissue Culture Supernatant

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab86473 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P 1/200 - 1/1000.
WB 1/500 - 1/2000. Predicted molecular weight: 33 kDa.
ELISA 1/10000.
ICC/IF 1/200 - 1/1000.

ターゲット情報

  • 機能
    Involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28 or CTLA-4 to this receptor.
  • 組織特異性
    Expressed on activated B-cells, macrophages and dendritic cells.
  • 配列類似性
    Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
    Contains 1 Ig-like V-type (immunoglobulin-like) domain.
  • 細胞内局在
    Membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Activation B7-1 antigen antibody
    • B lymphocyte activation antigen B7 antibody
    • B7 antibody
    • B7-1 antibody
    • B7-1 antigen antibody
    • B7.1 antibody
    • BB1 antibody
    • CD28 antigen ligand 1 antibody
    • CD28LG antibody
    • CD28LG1 antibody
    • CD80 antibody
    • CD80 antigen (CD28 antigen ligand 1, B7-1 antigen) antibody
    • CD80 antigen antibody
    • CD80 molecule antibody
    • CD80_HUMAN antibody
    • Costimulatory factor CD80 antibody
    • costimulatory molecule variant IgV-CD80 antibody
    • CTLA-4 counter-receptor B7.1 antibody
    • LAB7 antibody
    • T-lymphocyte activation antigen CD80 antibody
    see all

画像

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human tonsil tissue labelling CD80 with ab86473.

  • Confocal immunofluorescence analysis of BCBL-1 cells using ab86473 at 1/200 dilution (green), showing membrane localization. Blue: DRAQ5 fluorescent DNA dye.

参考文献

This product has been referenced in:
  • Meletta R  et al. Preclinical imaging of the co-stimulatory molecules CD80 and CD86 with indium-111-labeled belatacept in atherosclerosis. EJNMMI Res 6:1 (2016). Read more (PubMed: 26728358) »

See 1 Publication for this product

レビューと Q&A



ab86473: endotoxin level was not measured


ab130164: endotoxin level of the antibody solution was not determined, but the purification process was performed in a clean environment, thus we assume the endotoxin level is quite low....

Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

登録