Anti-CD8 + HLA Class II 抗体 [733 + LN3] (Dual color: FITC + PE) (ab1236)

製品の概要

  • 製品名Anti-CD8 + HLA Class II antibody [733 + LN3] (Dual color: FITC + PE)
  • 製品の詳細
    Mouse monoclonal [733 + LN3] to CD8 + HLA Class II (Dual color: FITC + PE)
  • 標識Dual color: FITC + PE
  • アプリケーション適用あり: Flow Cytmore details
  • 種交差性
    交差種: Human
  • 特記事項This product is a mixture of two clones: CD8 = Clone:733, Isotype:IgG1, Label:FITC HLA-DR = Clone:LN3, Isotype:IgG2b, Label:PE This product contains sodium azide, which under acid conditions yields hydrazoic acid, a toxic compound. Azide compounds should be diluted with running water before being discarded to avoid deposits in lead or copper plumbing where explosive conditions may develop.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab1236 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Flow Cyt
  • 追加情報Counting and identification of CD8+ T lymphocytes in human lysed whole peripheral blood or mononuclear cells separated by density gradient.
    Percentage count of CD8 activated lymphocytes.
    Studies of HIV (Human Immunodeficiency Virus) infection.

    CD8(FITC) / HLA-DR (PE) immunofluorescence analysis can be performed on a flow cytometerequipped with an excitation source of 488nm and fitted with logarithmic amplifiers.

    10µl ofCD8(FITC) / HLA-DR (PE) is sufficient for labelling 1x106 cells.
  • ターゲット情報

    • 関連性CD8: This antigen is present on human T suppressor/cytotoxic cell subtypes, that represents 20-36% of normal peripheral blood lymphocytes, and on NK cells subset (CD3-CD8+) and thymocytes. Patients with AIDS exhibit T cells lymphopenia, a loss of CD4+ lymphocytes and a relative increase in the CD8+ subtype and in the CD3+CD4-CD8- subtype. HLA-DR (human Class II histocompatibility antigen): This antigen is present on antigen presenting cells (APC), B cells, monocytes, thymic epithelial cells and macrophages. It is also expressed on activated T cells, but not on granulocytes, platelets or red blood cells. Resting T cells or endothelial cells can be induced to express HLA-DR antigens.
    • 細胞内局在Membrane; singlepass type I membrane protein.
    • 参照データベース

    Anti-CD8 + HLA Class II antibody [733 + LN3] (Dual color: FITC + PE) (ab1236) 使用論文

    ab1236 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab1236.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"