製品の概要

  • 製品名
    Anti-CD8 alpha antibody [CT-8] (Cy5 ®)
    CD8 alpha 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [CT-8] to CD8 alpha (Cy5 ®)
  • 標識
    Cy5 ®. Ex: 650nm, Em: 667nm
  • 特異性
    Recognizes chicken CD8a chain (34 kDa)
  • アプリケーション
    適用あり: Flow Cyt, IHC-Fr, IPmore details
  • 種交差性
    交差種: Chicken
  • 免疫原

    The details of the immunogen for this antibody are not available.

  • ポジティブ・コントロール
    • Chicken PBMC
  • 特記事項
    This product or portions thereof is manufactured under license from Carnegie Mellon University under U.S. Patent Number 5,268,486 and related patents. Cy and CyDye are trademarks of GE Healthcare Limited.

    Abcam is committed to meeting high standards of ethical manufacturing and as such, we will be discontinuing this product, which has been generated by the ascites method, within the next year. We are sorry for any inconvenience this may cause. If you would like help finding an alternative product, please do not hesitate to contact our scientific support team.

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Store at +4°C.
  • バッファー
    Preservative: 0.1% Sodium Azide
    Constituents: PBS and stabilising agent.
  • Concentration information loading...
  • 精製度
    IgG fraction
  • ポリ/モノ
    モノクローナル
  • クローン名
    CT-8
  • アイソタイプ
    IgG1
  • 軽鎖の種類
    kappa
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab82007 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Flow Cyt
IHC-Fr
IP
  • 追加情報
    Flow Cyt: Use 1µg for 106 cells.
    IHC-Fr (acetone): Use at an assay dependent dilution.
    IP: Use at an assay dependent dilution.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能
      Identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing. CD8 alpha chains binds to class I MHC molecules alpha-3 domains.
    • 関連疾患
      Defects in CD8A are a cause of familial CD8 deficiency (CD8 deficiency) [MIM:608957]. Familial CD8 deficiency is a novel autosomal recessive immunologic defect characterized by absence of CD8+ cells, leading to recurrent bacterial infections.
    • 配列類似性
      Contains 1 Ig-like V-type (immunoglobulin-like) domain.
    • 翻訳後修飾
      All of the five most carboxyl-terminal cysteines form inter-chain disulfide bonds in dimers and higher multimers, while the four N-terminal cysteines do not.
    • 細胞内局在
      Secreted and Cell membrane.
    • Information by UniProt
    • 別名
      • alpha polypeptide (p32) antibody
      • CD8 antibody
      • CD8 antigen alpha polypeptide antibody
      • CD8 antigen alpha polypeptide (p32) antibody
      • CD8a antibody
      • CD8A antigen antibody
      • CD8A molecule antibody
      • CD8A_HUMAN antibody
      • Leu2 antibody
      • Leu2 T lymphocyte antigen antibody
      • Ly3 antibody
      • LYT3 antibody
      • MAL antibody
      • OKT8 T cell antigen antibody
      • OTTHUMP00000160760 antibody
      • OTTHUMP00000160764 antibody
      • OTTHUMP00000203528 antibody
      • OTTHUMP00000203721 antibody
      • p32 antibody
      • T cell antigen Leu2 antibody
      • T cell co receptor antibody
      • T-cell surface glycoprotein CD8 alpha chain antibody
      • T-lymphocyte differentiation antigen T8/Leu-2 antibody
      • T8 T cell antigen antibody
      • T8/Leu-2 T-lymphocyte differentiation antigen antibody
      see all

    参考文献

    This product has been referenced in:
    • Chan MM  et al. Identification of the avian homologues of mammalian CD4 and CD8 antigens. J Immunol 140:2133-8 (1988). Flow Cyt, IP ; Chicken . Read more (PubMed: 3258329) »

    See 1 Publication for this product

    レビューと Q&A

    There are currently no Customer reviews or Questions for ab82007.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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