Anti-CD8 alpha 抗体 [53-6.7] (Phycoerythrin -Texas Red®) (ab25294)


  • 製品名Anti-CD8 alpha antibody [53-6.7] (Phycoerythrin -Texas Red®)
    CD8 alpha 一次抗体 製品一覧
  • 製品の詳細
    Rat monoclonal [53-6.7] to CD8 alpha (Phycoerythrin -Texas Red®)
  • 標識Phycoerythrin -Texas Red®. Ex: 496nm, Em: 613nm
  • 特異性ab25194 recognises CD8 alpha. In vivo and in vitro treatment with ab25294 effectively depletes CD8a+ cells. It also blocks allogeneic help specific for class I MHC antigens and T cell responses to IL-2.
  • アプリケーション適用あり: Flow Cyt, IHC-Fr, IPmore details
  • 種交差性
    交差種: Mouse
  • 免疫原

    The details of the immunogen for this antibody are not available.



Our Abpromise guarantee covers the use of ab25294 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Flow Cyt Use 0.2µg for 106 cells.
IHC-Fr Use at an assay dependent dilution.
IP Use at an assay dependent dilution.
In vivo and in vitro depletion of CD8alpha+ cells: Use at an assay dependent dilution.
Fractionation of CD8alpha+ T cells: Use at an assay dependent dilution.


  • 機能Identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing. CD8 alpha chains binds to class I MHC molecules alpha-3 domains.
  • 関連疾患Defects in CD8A are a cause of familial CD8 deficiency (CD8 deficiency) [MIM:608957]. Familial CD8 deficiency is a novel autosomal recessive immunologic defect characterized by absence of CD8+ cells, leading to recurrent bacterial infections.
  • 配列類似性Contains 1 Ig-like V-type (immunoglobulin-like) domain.
  • 翻訳後修飾All of the five most carboxyl-terminal cysteines form inter-chain disulfide bonds in dimers and higher multimers, while the four N-terminal cysteines do not.
  • 細胞内局在Secreted and Cell membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • alpha polypeptide (p32) antibody
    • CD8 antibody
    • CD8 antigen alpha polypeptide antibody
    • CD8 antigen alpha polypeptide (p32) antibody
    • CD8a antibody
    • CD8A antigen antibody
    • CD8A molecule antibody
    • CD8A_HUMAN antibody
    • Leu2 antibody
    • Leu2 T lymphocyte antigen antibody
    • Ly3 antibody
    • LYT3 antibody
    • MAL antibody
    • OKT8 T cell antigen antibody
    • OTTHUMP00000160760 antibody
    • OTTHUMP00000160764 antibody
    • OTTHUMP00000203528 antibody
    • OTTHUMP00000203721 antibody
    • p32 antibody
    • T cell antigen Leu2 antibody
    • T cell co receptor antibody
    • T-cell surface glycoprotein CD8 alpha chain antibody
    • T-lymphocyte differentiation antigen T8/Leu-2 antibody
    • T8 T cell antigen antibody
    • T8/Leu-2 T-lymphocyte differentiation antigen antibody
    see all

Anti-CD8 alpha antibody [53-6.7] (Phycoerythrin -Texas Red®) (ab25294) 使用論文

This product has been referenced in:
  • Tomov VT  et al. Persistent enteric murine norovirus infection is associated with functionally suboptimal virus-specific CD8 T cell responses. J Virol 87:7015-31 (2013). Read more (PubMed: 23596300) »
  • Hall JM  et al. Chronic psychological stress suppresses contact hypersensitivity: Potential roles of dysregulated cell trafficking and decreased IFN-? production. Brain Behav Immun N/A:N/A (2013). Mouse . Read more (PubMed: 24184400) »

See all 4 Publications for this product

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We do not have set expiration dates for our products. Most antibodies are stable and can last for anywhere from a few months to several years if stored properly, so we strongly recommend that you follow the storage ...

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