Anti-CD8 alpha 抗体 [53-6.7] (Allophycocyanin/Cy7 ®) (ab25456)


  • 製品名Anti-CD8 alpha antibody [53-6.7] (Allophycocyanin/Cy7 ®)
    CD8 alpha 一次抗体 製品一覧
  • 製品の詳細
    Rat monoclonal [53-6.7] to CD8 alpha (Allophycocyanin/Cy7 ®)
  • 標識Allophycocyanin/Cy7 ®. Ex: 650nm, Em: 774nm
  • 特異性ab25456 recognises a chain of the murine CD8 heterodimer.
  • アプリケーション適用あり: Flow Cyt, IHC-Fr, IP, Functional Studiesmore details
  • 種交差性
    交差種: Mouse
  • 免疫原

    The details of the immunogen for this antibody are not available.

  • 特記事項This product or portions thereof is manufactured under license from Carnegie Mellon University under U.S. Patent Number 5,268,486 and related patents. Cy and CyDye are trademarks of GE Healthcare Limited.

    This antibody blocks allogeneic help specific for class I MHC antigens and T cell responses to IL-2.



Our Abpromise guarantee covers the use of ab25456 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Flow Cyt Use 0.2µg for 106 cells.
IHC-Fr Use at an assay dependent concentration.

Acetone fixed.

IP Use at an assay dependent concentration.
Functional Studies Use at an assay dependent concentration.

In vivo and in vitro depletion of CD8α+ cells. Fractionation of CD8α+ T cells.


  • 機能Identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing. CD8 alpha chains binds to class I MHC molecules alpha-3 domains.
  • 関連疾患Defects in CD8A are a cause of familial CD8 deficiency (CD8 deficiency) [MIM:608957]. Familial CD8 deficiency is a novel autosomal recessive immunologic defect characterized by absence of CD8+ cells, leading to recurrent bacterial infections.
  • 配列類似性Contains 1 Ig-like V-type (immunoglobulin-like) domain.
  • 翻訳後修飾All of the five most carboxyl-terminal cysteines form inter-chain disulfide bonds in dimers and higher multimers, while the four N-terminal cysteines do not.
  • 細胞内局在Secreted and Cell membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • alpha polypeptide (p32) antibody
    • CD8 antibody
    • CD8 antigen alpha polypeptide antibody
    • CD8 antigen alpha polypeptide (p32) antibody
    • CD8a antibody
    • CD8A antigen antibody
    • CD8A molecule antibody
    • CD8A_HUMAN antibody
    • Leu2 antibody
    • Leu2 T lymphocyte antigen antibody
    • Ly3 antibody
    • LYT3 antibody
    • MAL antibody
    • OKT8 T cell antigen antibody
    • OTTHUMP00000160760 antibody
    • OTTHUMP00000160764 antibody
    • OTTHUMP00000203528 antibody
    • OTTHUMP00000203721 antibody
    • p32 antibody
    • T cell antigen Leu2 antibody
    • T cell co receptor antibody
    • T-cell surface glycoprotein CD8 alpha chain antibody
    • T-lymphocyte differentiation antigen T8/Leu-2 antibody
    • T8 T cell antigen antibody
    • T8/Leu-2 T-lymphocyte differentiation antigen antibody
    see all

Anti-CD8 alpha antibody [53-6.7] (Allophycocyanin/Cy7 ®) (ab25456) 使用論文

ab25456 has not yet been referenced specifically in any publications.

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