製品の概要

  • 製品名
    Anti-CD73 antibody [10f1]
    CD73 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [10f1] to CD73
  • 特異性
    This antibody reacts specifically with human 5'-nucleotidase cN-II (63kDa).
  • アプリケーション
    適用あり: WB, ICC, ICC/IFmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant full length protein corresponding to Human CD73.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab59462 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/200 - 1/1000. Predicted molecular weight: 63 kDa.
ICC 1/200 - 1/1000.
ICC/IF Use at an assay dependent concentration. PubMed: 20601304

ターゲット情報

  • 機能
    Hydrolyzes extracellular nucleotides into membrane permeable nucleosides.
  • 関連疾患
    Defects in NT5E are the cause of calcification of joints and arteries (CAJA) [MIM:211800]. A condition characterized by adult-onset calcification of the lower extremity arteries, including the iliac, femoral and tibial arteries, and hand and foot capsule joints. Age of onset has been reported as early as the second decade of life, usually involving intense joint pain or calcification in the hands.
  • 配列類似性
    Belongs to the 5'-nucleotidase family.
  • 細胞内局在
    Cell membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 5' NT antibody
    • 5' nucleotidase (CD73) antibody
    • 5' nucleotidase precursor antibody
    • 5' nucleotidase, ecto antibody
    • 5' nucleotidase, ecto (CD73) antibody
    • 5'-NT antibody
    • 5'-nucleotidase antibody
    • 5NTD_HUMAN antibody
    • CD73 antibody
    • CD73 antigen antibody
    • E5NT antibody
    • Ecto 5' nucleotidase antibody
    • Ecto-5'-nucleotidase antibody
    • eN antibody
    • eNT antibody
    • NT antibody
    • NT5 antibody
    • NT5E antibody
    • NTE antibody
    • Purine 5 Prime Nucleotidase antibody
    see all

参考文献

This product has been referenced in:
  • Kopher RA  et al. Human embryonic stem cell-derived CD34+ cells function as MSC progenitor cells. Bone 47:718-28 (2010). ICC/IF ; Human . Read more (PubMed: 20601304) »

See 1 Publication for this product

レビューと Q&A

Abcam has not validated the combination of species/application used in this Abreview.
Application
Flow Cytometry
Sample
Horse Cell (Mesenchymal stem cells from umbililical cord blood)
Specification
Mesenchymal stem cells from umbililical cord blood
Preparation
Cell harvesting/tissue preparation method: Percoll gradient isolation from umbilical cord blood followed by selective cultivation
Sample buffer: DMEM +1% BSA
Permeabilization
No
Gating Strategy
based on FS/SS pattern , mesenchymal stem cells without debris
Username

Mrs. Kristel Demeyere

Verified customer

投稿 Oct 22 2009

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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