Anti-CD70 抗体 [TAN 1-7] (ab108482)
Key features and details
- Rat monoclonal [TAN 1-7] to CD70
- Suitable for: ELISA, ICC/IF, Flow Cyt
- Reacts with: Mouse
- Isotype: IgG2a
製品の概要
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製品名
Anti-CD70 antibody [TAN 1-7]
CD70 一次抗体 製品一覧 -
製品の詳細
Rat monoclonal [TAN 1-7] to CD70 -
由来種
Rat -
特異性
This antibody is a non-depleting mAb that blocks the CD70-CD27 interaction. -
アプリケーション
適用あり: ELISA, ICC/IF, Flow Cytmore details -
種交差性
交差種: Mouse -
免疫原
Recombinant mouse CD70 (extracellular domain, aa residues 41-195).
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ポジティブ・コントロール
- Activated dendritic cells.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
バッファー
Preservative: 0.02% Sodium azide
Constituent: 99.98% PBS -
Concentration information loading...
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精製度
Protein A/G purified -
ポリ/モノ
モノクローナル -
クローン名
TAN 1-7 -
ミエローマ
NS0 -
アイソタイプ
IgG2a -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab108482の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
ELISA |
Use at an assay dependent concentration.
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ICC/IF |
Use at an assay dependent concentration.
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Flow Cyt |
Use at an assay dependent concentration.
ab18450 - Rat monoclonal IgG2a, is suitable for use as an isotype control with this antibody. |
特記事項 |
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ELISA
Use at an assay dependent concentration. |
ICC/IF
Use at an assay dependent concentration. |
Flow Cyt
Use at an assay dependent concentration. ab18450 - Rat monoclonal IgG2a, is suitable for use as an isotype control with this antibody. |
ターゲット情報
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機能
Cytokine that binds to CD27. Plays a role in T-cell activation. Induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells. -
配列類似性
Belongs to the tumor necrosis factor family. -
細胞内局在
Membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 21948 Mouse
- SwissProt: O55237 Mouse
- Unigene: 42228 Mouse
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別名
- CD 27L antibody
- CD 70 antibody
- CD27 L antibody
see all
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (2)
ab108482 は 2 報の論文で使用されています。
- Taraban VY et al. Invariant NKT cells promote CD8+ cytotoxic T cell responses by inducing CD70 expression on dendritic cells. J Immunol 180:4615-20 (2008). PubMed: 18354184
- Rowley TF & Al-Shamkhani A Stimulation by soluble CD70 promotes strong primary and secondary CD8+ cytotoxic T cell responses in vivo. J Immunol 172:6039-46 (2004). PubMed: 15128787