製品の概要

  • 製品名Anti-CD68 antibody [Y1/82A] (Biotin)
    CD68 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [Y1/82A] to CD68 (Biotin)
  • 標識Biotin
  • アプリケーション適用あり: Flow Cytmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Purified Human CD68

  • ポジティブ・コントロール
    • Normal human peripheral blood cells/leukocytes

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • バッファーPreservative: Less than or equal to 0.09% Sodium Azide
    Constituents: PBS, pH 7.2
  • Concentration information loading...
  • 精製度Protein G purified
  • ポリ/モノモノクローナル
  • クローン名Y1/82A
  • アイソタイプIgG2b
  • 軽鎖の種類kappa
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab95564 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Flow Cyt Use 0.125µg for 105-8 cells. Staining the cell sample in a final volume of 100 µL is recommended



ab18418-Mouse monoclonal IgG2b, is suitable for use as an isotype control with this antibody.

ターゲット情報

  • 機能Could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells.
  • 組織特異性Highly expressed by blood monocytes and tissue macrophages. Also expressed in lymphocytes, fibroblasts and endothelial cells. Expressed in many tumor cell lines which could allow them to attach to selectins on vascular endothelium, facilitating their dissemination to secondary sites.
  • 配列類似性Belongs to the LAMP family.
  • 翻訳後修飾N- and O-glycosylated.
  • 細胞内局在Cell membrane and Endosome membrane. Lysosome membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CD 68 antibody
    • CD68 antibody
    • CD68 antigen antibody
    • CD68 molecule antibody
    • CD68_HUMAN antibody
    • DKFZp686M18236 antibody
    • gp11 antibody
    • Gp110 antibody
    • LAMP4 antibody
    • Macrophage antigen CD68 (microsialin) antibody
    • MACROPHAGE ANTIGEN CD68 antibody
    • Macrosialin antibody
    • SCARD1 antibody
    • Scavenger receptor class D member 1 antibody
    see all

Anti-CD68 antibody [Y1/82A] (Biotin) 画像

  • Flow cytometry staining of normal human peripheral blood cells with Anti-Mouse CD11b FITC and 0.06 µg of Mouse IgG2b ? Isotype Control Biotin (left) or 0.06 µg of ab95564 (right) followed by Streptavidin PE. Cells in the lymphocyte gate were used for analysis.

Anti-CD68 antibody [Y1/82A] (Biotin) (ab95564) 使用論文

This product has been referenced in:
  • Davey FR  et al. Monoclonal antibody (Y1/82A) with specificity towards peripheral blood monocytes and tissue macrophages. J Clin Pathol 41:753-8 (1988). Read more (PubMed: 2457604) »

See 1 Publication for this product

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