製品の概要

  • 製品名Anti-CD68 antibody
    CD68 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to CD68
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Rat, Pig
  • 免疫原

    Synthetic peptide corresponding to a region within internal sequence amino acids 162-211 (EAWGISVLNP NKTKVQGSCE GAHPHLLLSF PYGHLSFGFM QDLQQKVVYL) of Human CD68 (NP_001035148).

  • ポジティブ・コントロール
    • Jurkat cell lysate.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • バッファーConstituents: 97% PBS, 2% Sucrose
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab125475 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 35 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能Could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells.
  • 組織特異性Highly expressed by blood monocytes and tissue macrophages. Also expressed in lymphocytes, fibroblasts and endothelial cells. Expressed in many tumor cell lines which could allow them to attach to selectins on vascular endothelium, facilitating their dissemination to secondary sites.
  • 配列類似性Belongs to the LAMP family.
  • 翻訳後修飾N- and O-glycosylated.
  • 細胞内局在Cell membrane and Endosome membrane. Lysosome membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CD 68 antibody
    • CD68 antibody
    • CD68 antigen antibody
    • CD68 molecule antibody
    • CD68_HUMAN antibody
    • DKFZp686M18236 antibody
    • gp11 antibody
    • Gp110 antibody
    • LAMP4 antibody
    • Macrophage antigen CD68 (microsialin) antibody
    • MACROPHAGE ANTIGEN CD68 antibody
    • Macrosialin antibody
    • SCARD1 antibody
    • Scavenger receptor class D member 1 antibody
    see all

Anti-CD68 antibody 画像

  • Anti-CD68 antibody (ab125475) at 1 µg/ml + Jurkat cell lysate at 10 µg

    Predicted band size : 35 kDa

Anti-CD68 antibody (ab125475) 使用論文

This product has been referenced in:
  • Chen M  et al. RAGE regulates immune cell infiltration and angiogenesis in choroidal neovascularization. PLoS One 9:e89548 (2014). Mouse . Read more (PubMed: 24586862) »

See 1 Publication for this product

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I can confirm that this product is free of preservatives such as sodium azide, etc. This product buffer only contains 1X PBS + 2% sucrose and should be OK for use in cell culture experiments (although only WB is o...

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