製品の概要

  • 製品名
    Anti-CD68 antibody
    CD68 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to CD68
  • 由来種
    Rabbit
  • アプリケーション
    適用あり: IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide corresponding to a region from internal amino acids of Human CD68.

  • ポジティブ･コントロール
    • Human Tonsil tissue

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファー
    pH: 7.60
    Preservative: 0.1% Sodium azide
    Constituents: 99% PBS, 1% BSA
  • Concentration information loading...
  • 精製度
    Immunogen affinity purified
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab125157 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P 1/100. Boil tissue section in EDTA buffer for 10 min followed by cooling at RT for 20 min.

ターゲット情報

  • 機能
    Could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells.
  • 組織特異性
    Highly expressed by blood monocytes and tissue macrophages. Also expressed in lymphocytes, fibroblasts and endothelial cells. Expressed in many tumor cell lines which could allow them to attach to selectins on vascular endothelium, facilitating their dissemination to secondary sites.
  • 配列類似性
    Belongs to the LAMP family.
  • 翻訳後修飾
    N- and O-glycosylated.
  • 細胞内局在
    Cell membrane and Endosome membrane. Lysosome membrane.
  • Information by UniProt
  • 参照データベース
    • 別名
      • CD 68 antibody
      • CD68 antibody
      • CD68 antigen antibody
      • CD68 molecule antibody
      • CD68_HUMAN antibody
      • DKFZp686M18236 antibody
      • gp11 antibody
      • Gp110 antibody
      • LAMP4 antibody
      • Macrophage antigen CD68 (microsialin) antibody
      • MACROPHAGE ANTIGEN CD68 antibody
      • Macrosialin antibody
      • SCARD1 antibody
      • Scavenger receptor class D member 1 antibody
      see all

    画像

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD68 antibody (ab125157)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD68 antibody (ab125157)
      Staining of CD68 in Paraffin-embedded Human tonsil tissue by Immunohistochemistry using ab125157 at a dilution of 1/100.

    プロトコール

    参考文献

    This product has been referenced in:
    • Asahchop EL  et al. Reduced antiretroviral drug efficacy and concentration in HIV-infected microglia contributes to viral persistence in brain. Retrovirology 14:47 (2017). IHC-P ; Human . Read more (PubMed: 29037245) »
    • Sindhu S  et al. Obesity Is a Positive Modulator of IL-6R and IL-6 Expression in the Subcutaneous Adipose Tissue: Significance for Metabolic Inflammation. PLoS One 10:e0133494 (2015). IHC-P ; Human . Read more (PubMed: 26200663) »

    See all 3 Publications for this product

    ab125157 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

    レビューと Q&A

    レビューを送る 質問を送る

    2 reviews or Q&A

    10
    Votes: Highest First

    könnten Sie mir bitte die Konzentrationsangabe des rabbit anti-human CD68 Antikörpers mit der Bestellnummer ab125157 und der Lot-Nr. GR107394-1 zusenden?

    Vielen Dank für Ihre Anfrage.

    Die Konzentration für das von Ihnen genannte Lot-Nr. beträgt 0.021 mg/ml.

    Ich hoffe, dies hilft Ihnen weiter. Bitte zögern Sie nicht, sich wieder bei uns zu melden, falls Sie weite...

    Read More

    Dear Abcam Tech Support,



    A customer contacted us with the following enquiry:



    “I just rang to get a quote for following two Abcam antibodies against CD68:

    ab125157 (100 uL) which recognises ...

    Read More

    Thank you for your inquiry.

    I agree with your customer that there is not much difference with both antibodies and that we do not have any customer feedback for them yet.

    I can confirm that both are covered by our guarantee for IHC-P...

    Read More

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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