製品の概要
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製品名Anti-CD68 antibody
CD68 一次抗体 製品一覧 -
製品の詳細Rabbit polyclonal to CD68
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アプリケーション適用あり: IHC-Pmore details
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種交差性交差種: Human
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免疫原
Synthetic peptide corresponding to a region from internal amino acids of Human CD68.
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ポジティブ･コントロール
- Human Tonsil tissue
製品の特性
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製品の状態Liquid
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保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
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バッファーpH: 7.60
Preservative: 0.1% Sodium azide
Constituents: 99% PBS, 1% BSA -
Concentration information loading... -
精製度Immunogen affinity purified
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ポリ/モノポリクローナル
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アイソタイプIgG
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研究分野
関連製品
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Compatible Secondaries
アプリケーション
Our Abpromise guarantee covers the use of ab125157 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| IHC-P | 1/100. Boil tissue section in EDTA buffer for 10 min followed by cooling at RT for 20 min. |
ターゲット情報
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機能Could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells.
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組織特異性Highly expressed by blood monocytes and tissue macrophages. Also expressed in lymphocytes, fibroblasts and endothelial cells. Expressed in many tumor cell lines which could allow them to attach to selectins on vascular endothelium, facilitating their dissemination to secondary sites.
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配列類似性Belongs to the LAMP family.
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翻訳後修飾N- and O-glycosylated.
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細胞内局在Cell membrane and Endosome membrane. Lysosome membrane.
- Information by UniProt
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参照データベース
- Entrez Gene: 968 Human
- Omim: 153634 Human
- SwissProt: P34810 Human
- Unigene: 647419 Human
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別名
- CD 68 antibody
- CD68 antibody
- CD68 antigen antibody
see all
Anti-CD68 antibody 画像
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD68 antibody (ab125157)Staining of CD68 in Paraffin-embedded Human tonsil tissue by Immunohistochemistry using ab125157 at a dilution of 1/100.
Anti-CD68 antibody (ab125157) 使用論文
This product has been referenced in:
- Sindhu S et al. Obesity Is a Positive Modulator of IL-6R and IL-6 Expression in the Subcutaneous Adipose Tissue: Significance for Metabolic Inflammation. PLoS One 10:e0133494 (2015). IHC-P ; Human . Read more (PubMed: 26200663) »
- Zeng WJ et al. Quantum dot-based multiplexed imaging in malignant ascites: a new model for malignant ascites classification. Int J Nanomedicine 10:1759-68 (2015). IHC-P ; Human . Read more (PubMed: 25784803) »
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"