Anti-CD62E 抗体 [UZ6] (ab2497)
Key features and details
- Rat monoclonal [UZ6] to CD62E
- Suitable for: ICC/IF
- Reacts with: Mouse
- Isotype: IgG2b
製品の概要
-
製品名
Anti-CD62E antibody [UZ6]
CD62E 一次抗体 製品一覧 -
製品の詳細
Rat monoclonal [UZ6] to CD62E -
由来種
Rat -
アプリケーション
適用あり: ICC/IFmore details -
種交差性
交差種: Mouse -
ポジティブ・コントロール
- ICC/IF: CHO-cells transfected with E-Selectin.
-
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
-
製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
Preservative: 0.09% Sodium azide
Constituent: PBS -
Concentration information loading...
-
精製度
Protein A purified -
ポリ/モノ
モノクローナル -
クローン名
UZ6 -
ミエローマ
Sp2/0 -
アイソタイプ
IgG2b -
研究分野
関連製品
-
Compatible Secondaries
-
Conjugation kits
-
Isotype control
-
Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab2497の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
ICC/IF |
Use at an assay dependent concentration.
|
特記事項 |
---|
ICC/IF
Use at an assay dependent concentration. |
ターゲット情報
-
機能
Cell-surface glycoprotein having a role in immunoadhesion. Mediates in the adhesion of blood neutrophils in cytokine-activated endothelium through interaction with PSGL1/SELPLG. May have a role in capillary morphogenesis. -
配列類似性
Belongs to the selectin/LECAM family.
Contains 1 C-type lectin domain.
Contains 1 EGF-like domain.
Contains 6 Sushi (CCP/SCR) domains. -
細胞内局在
Membrane. - Information by UniProt
-
参照データベース
- Entrez Gene: 20339 Mouse
- SwissProt: Q00690 Mouse
- Unigene: 5245 Mouse
-
別名
- CD26E antibody
- CD62 antigen-like family member E antibody
- CD62E antibody
see all
プロトコール
データシートおよび資料
-
SDS download
-
Datasheet download
参考文献 (6)
ab2497 は 6 報の論文で使用されています。
- Schimmel K et al. Combined high-throughput library screening and next generation RNA sequencing uncover microRNAs controlling human cardiac fibroblast biology. J Mol Cell Cardiol 150:91-100 (2021). PubMed: 33127387
- Sakamoto T et al. Pharmacological inhibition of Mint3 attenuates tumour growth, metastasis, and endotoxic shock. Commun Biol 4:1165 (2021). PubMed: 34621018
- Cao H et al. The protective effect of vitexinin septic encephalopathy by reducing leukocyte-endothelial adhesion and inflammatory response. Ann Palliat Med 9:2079-2089 (2020). PubMed: 32692224
- Meng ZD et al. Effects of RNA interference-mediated E-selectin gene silencing on cell adhesion molecule expression and cell-cell adhesion in vascular endothelial cells in mice with immunologic contact urticaria. J Cell Biochem 120:115-125 (2019). PubMed: 30206961
- Sapieha P et al. 5-Lipoxygenase metabolite 4-HDHA is a mediator of the antiangiogenic effect of ?-3 polyunsaturated fatty acids. Sci Transl Med 3:69ra12 (2011). PubMed: 21307302
- Hammel M et al. Species-specific and conserved epitopes on mouse and human E-selectin important for leukocyte adhesion. Exp Cell Res 269:266-74 (2001). PubMed: 11570819