製品の概要

  • 製品名Anti-CD62E antibody [ENA1] (Biotin)
    CD62E 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [ENA1] to CD62E (Biotin)
  • 標識Biotin
  • 特異性This antibody reacts with human endothelial cells activated with TNF, IL1 or endotoxin. It was found to react also with cells transfected with the the E-selectin gene.
  • アプリケーション適用あり: IHC-Fr, ICC/IFmore details
  • 種交差性
    交差種: Human, Chimpanzee, Baboon, Cynomolgus Monkey, Rhesus monkey
  • 免疫原

    Tissue/ cell preparation containing human CD3

  • ポジティブ・コントロール
    • Endothelial cells or a small fresh skin biopsy after incubation with TNF, IL1 or LPS.
  • 特記事項


    This antibody is useful for the staining of CD62E expressing endothelial cells. This antibody inhibits the adhesion of granulocytes both neutrophilic and eosinophilic.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab36688 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-Fr Use at an assay dependent concentration.

Fixed with acetone, followed by incubation for 10 min in chloroform.

ICC/IF Use at an assay dependent concentration.

Fixed with paraformaldehyde.

ターゲット情報

  • 機能Cell-surface glycoprotein having a role in immunoadhesion. Mediates in the adhesion of blood neutrophils in cytokine-activated endothelium through interaction with PSGL1/SELPLG. May have a role in capillary morphogenesis.
  • 配列類似性Belongs to the selectin/LECAM family.
    Contains 1 C-type lectin domain.
    Contains 1 EGF-like domain.
    Contains 6 Sushi (CCP/SCR) domains.
  • 細胞内局在Membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CD26E antibody
    • CD62 antigen-like family member E antibody
    • CD62E antibody
    • E selectin antibody
    • E-selectin antibody
    • ELAM antibody
    • ELAM-1 antibody
    • ELAM1 antibody
    • Endothelial adhesion molecule 1 antibody
    • Endothelial leukocyte adhesion molecule 1 antibody
    • ESEL antibody
    • LECAM2 antibody
    • Leukocyte-endothelial cell adhesion molecule 2 antibody
    • LYAM2_HUMAN antibody
    • Sele antibody
    • Selectin E antibody
    see all

Anti-CD62E antibody [ENA1] (Biotin) (ab36688) 使用論文

This product has been referenced in:
  • Leeuwenberg JF  et al. Adhesion of polymorphonuclear cells to human endothelial cells. Adhesion-molecule-dependent, and Fc receptor-mediated adhesion-molecule-independent mechanisms. Clin Exp Immunol 81:496-500 (1990). Read more (PubMed: 1697800) »
  • Leeuwenberg JF  et al. Functional polymorphism of IgG FcRII (CD32) on human neutrophils. Immunology 71:301-4 (1990). Read more (PubMed: 2146215) »

See all 3 Publications for this product

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