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RabMAb

Anti-CD6 抗体 [EPR4057] (ab109217)

製品の概要

  • 製品名
    Anti-CD6 antibody [EPR4057]
    CD6 一次抗体 製品一覧
  • 製品の詳細
    Rabbit monoclonal [EPR4057] to CD6
  • アプリケーション
    適用あり: WB, IP, IHC-P, ICCmore details
    適用なし: Flow Cyt
  • 種交差性
    交差種: Human
  • 免疫原

    A synthetic peptide corresponding to residues in Human CD6.

  • ポジティブ・コントロール
    • WB: Jurkat, Human tonsil, PBMC and HuT-78 lysates IHC-P: Human tonsil and Human lymphocytes infiltrating colon tissues
  • 特記事項

    This product is a recombinant rabbit monoclonal antibody.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab109217 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/1000 - 1/10000. Detects a band of approximately 90-130 kDa (predicted molecular weight: 72 kDa).
IP 1/10 - 1/100.
IHC-P 1/100 - 1/250. Antigen retrieval is recommended.
ICC 1/100 - 1/250.
  • 追加情報
    Is unsuitable for Flow Cyt.
  • ターゲット情報

    • 機能
      Involved in cell adhesion. Binds to CD166.
    • 組織特異性
      Expressed by thymocytes, mature T-cells, a subset of B-cells known as B-1 cells, and by some cells in the brain.
    • 配列類似性
      Contains 3 SRCR domains.
    • 翻訳後修飾
      After T-cell activation, becomes hyperphosphorylated on Ser and Thr residues and phosphorylated on Tyr residues.
      Contains intrachain disulfide bond(s).
    • 細胞内局在
      Membrane.
    • Information by UniProt
    • 参照データベース
    • 別名
      • CD_antigen=CD6 antibody
      • CD6 antibody
      • CD6 antigen Tp120 antibody
      • CD6 molecule antibody
      • CD6_HUMAN antibody
      • FLJ44171 antibody
      • OX52 antibody
      • T cell differentiation antigen CD6 antibody
      • T-cell differentiation antigen CD6 antibody
      • T12 antibody
      • TP120 antibody
      see all

    画像

    • All lanes : Anti-CD6 antibody [EPR4057] (ab109217) at 1/1000 dilution

      Lane 1 : Jurkat lysates
      Lane 2 : Human tonsil lysates
      Lane 3 : PBMC lysates
      Lane 4 : HuT-78 lysates

      Lysates/proteins at 10 µg per lane.

      Secondary
      HRP labelled goat anti-rabbit at 1/2000 dilution

      Predicted band size : 72 kDa
      Observed band size : 90-130 kDa (why is the actual band size different from the predicted?)
    • ab109217, at a 1/100 dilution, staining CD6 in paraffin embedded Human tonsil tissue by Immunohistochemistry.
    • ab109217, at a 1/100 dilution, staining CD6 in paraffin embedded Human lymphocytes infiltrating colon tissue by Immunohistochemistry.
    • ab109217 showing negative staining in Skeletal muscle tissue.

    • ab109217 showing negative staining in Normal brain tissue.

    • ab109217 showing negative staining in Normal kidney tissue.

    • ab109217 showing negative staining in Normal uterus tissue.

    参考文献

    ab109217 has not yet been referenced specifically in any publications.

    レビューと Q&A

    There are currently no Customer reviews or Questions for ab109217.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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