製品の概要

  • 製品名
    Anti-CD57 antibody [NK-1] (PE/Cy5®)
    CD57 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [NK-1] to CD57 (PE/Cy5®)
  • 標識
    PE/Cy5®. Ex: 496nm, Em: 670nm
  • アプリケーション
    適用あり: Flow Cyt, IHC-Fr, IPmore details
  • 種交差性
    交差種: Human
  • 免疫原

    The details of the immunogen for this antibody are not available.

  • 特記事項
    This product or portions thereof is manufactured under license from Carnegie Mellon University under U.S. Patent Number 5,268,486 and related patents. Cy and CyDye are trademarks of GE Healthcare Limited.

    Abcam is committed to meeting high standards of ethical manufacturing and has decided to discontinue this product by June 2019 as it has been generated by the ascites method. We are sorry for any inconvenience this may cause. 

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Store at +4°C.
  • バッファー
    Preservative: 0.09% Sodium Azide
    Constituents: 16% Sucrose, 0.2% Gelatin, PBS; Stabilizing agent
  • Concentration information loading...
  • 精製度
    Purified IgM
  • ポリ/モノ
    モノクローナル
  • クローン名
    NK-1
  • アイソタイプ
    IgM
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab25445 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Flow Cyt Use 10µl for 106 cells.
IHC-Fr Use at an assay dependent dilution.
IP Use at an assay dependent dilution.

ターゲット情報

  • 機能
    Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on glycoproteins. Can also play a role in glycosaminoglycan biosynthesis. Substrates include asialo-orosomucoid (ASOR), asialo-fetuin, and asialo-neural cell adhesion molecule. Requires sphingomyelin for activity: stearoyl-sphingomyelin was the most effective, followed by palmitoyl-sphingomyelin and lignoceroyl-sphingomyelin. Activity was demonstrated only for sphingomyelin with a saturated fatty acid and not for that with an unsaturated fatty acid, regardless of the length of the acyl group.
  • 組織特異性
    Mainly expressed in the brain.
  • パスウェイ
    Protein modification; protein glycosylation.
  • 配列類似性
    Belongs to the glycosyltransferase 43 family.
  • 細胞内局在
    Golgi apparatus membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 3-glucuronyltransferase 1 antibody
    • 3-glucuronyltransferase antibody
    • B3GA1_HUMAN antibody
    • B3gat1 antibody
    • Beta 1 3 glucuronyltransferase 1 antibody
    • Beta-1 antibody
    • Beta-1,3-glucuronyltransferase 1 antibody
    • CD 57 antibody
    • CD57 antibody
    • CD57 antigen antibody
    • Galactosylgalactosylxylosylprotein 3 beta glucuronosyltransferase 1 antibody
    • Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 antibody
    • GlcAT P antibody
    • GlcAT-P antibody
    • GLCATP antibody
    • GlcUAT P antibody
    • GlcUAT-P antibody
    • GlcUATP antibody
    • Glucuronosyltransferase P antibody
    • HNK 1 antibody
    • HNK1 antibody
    • LEU 7 antibody
    • LEU7 antibody
    • LEU7 antigen antibody
    • NK 1 antibody
    • NK1 antibody
    • UDP GlcUA glycoprotein beta 1 3 glucuronyltransferase antibody
    • UDP-GlcUA:glycoprotein beta-1 antibody
    see all

参考文献

This product has been referenced in:
  • Jilek S  et al. HLA-B7-restricted EBV-specific CD8+ T cells are dysregulated in multiple sclerosis. J Immunol 188:4671-80 (2012). Human . Read more (PubMed: 22461701) »
  • Lopez-Vergès S  et al. Expansion of a unique CD57?NKG2Chi natural killer cell subset during acute human cytomegalovirus infection. Proc Natl Acad Sci U S A 108:14725-32 (2011). IF ; Human . Read more (PubMed: 21825173) »

See all 3 Publications for this product

レビューと Q&A

Thank you for contacting us.


Spectral Red is a PE/CY5 tandem conjugate. They are the same fluorophore but have different names.

I hope this information is helpful to you. Please do not hesitate to contact us if you need any m...

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Thank you for contacting us.

I have contacted our lab who have suggested IgM, [11E10] (Spectral Red) - Isotype Control as a suitable isotype control for ab25445. We have now added this item to our catalogue, reference number ab151937 (http:/...

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Thank you for contacting us.

I am very sorry that we do not stock this product and understand your frustration. I will contact the lab to see whether we could provide this isotype control and if so if it can be added to the catalogue. I will...

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Thank you for your inquiry.

Unfortunately, we do not have any isotype control mouse IgM PE-Cy5 conjugated available in our catalog.
I would like to recommend checking the Biocompare website which has an excellent antibody search facilit...

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Thanks for your reply. My colleague is out of the office today but I'll be happy to assist you untl she returns.

I expect that it will take 1-2 weeks to get this antibody to you. I'm currently working on getting a new lot, and we will send it...

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Thank you for contacting us.


The lab has informed me that ab25445is designed so that very minimal (typically <3%) FL2/FL3 compensation is required to remove any bleed in the PE channel. I hope this helps, please let me know if you need a...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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