Anti-CD48 抗体 [HM48-1] (Phycoerythrin) (ab95608)

製品の概要

  • 製品名
    Anti-CD48 antibody [HM48-1] (Phycoerythrin)
    CD48 一次抗体 製品一覧
  • 製品の詳細
    Armenian Hamster monoclonal [HM48-1] to CD48 (Phycoerythrin)
  • 標識
    Phycoerythrin. Ex: 488nm, Em: 575nm
  • アプリケーション
    適用あり: ICC/IF, Flow Cytmore details
  • 種交差性
    交差種: Mouse
  • 免疫原

    Mouse T lymphoma MBL2

  • ポジティブ・コントロール
    • C57BL/6 splenocytes
  • 特記事項


    HM48-1 is reported to modulate in vitro and in vivo CD48 functions including blocking the CD48/CD2 and CD48/CD244 interactions, inhibiting the proliferative response of mitogen-activated spleen cells, providing a costimulation signal for T cells activated in vitro through their TCR, and prolonging cardiac allograft survival in vivo.

    Excitation: 488 nm Emission: 575 nm.

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Store at +4°C.
  • バッファー
    Preservative: 0.09% Sodium Azide
    Constituents: PBS, 150mM Sodium chloride, pH 7.2
  • Concentration information loading...
  • 精製度
    Protein G purified
  • 一次抗体 備考
    HM48-1 is reported to modulate in vitro and in vivo CD48 functions including blocking the CD48/CD2 and CD48/CD244 interactions, inhibiting the proliferative response of mitogen-activated spleen cells, providing a costimulation signal for T cells activated in vitro through their TCR, and prolonging cardiac allograft survival in vivo.
  • ポリ/モノ
    モノクローナル
  • クローン名
    HM48-1
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab95608 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ICC/IF Use at an assay dependent concentration.
Flow Cyt Use 0.06-0.125µg for 105-8 cells. Staining the cell sample in a final volume of 100 µL is recommended.



ab101026-Armenian Hamster monoclonal IgG, is suitable for use as an isotype control with this antibody.

ターゲット情報

  • 機能
    Ligand for CD2. Might facilitate interaction between activated lymphocytes. Probably involved in regulating T-cell activation.
  • 配列類似性
    Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
    Contains 1 Ig-like V-type (immunoglobulin-like) domain.
  • 細胞内局在
    Cell membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Antigen CD48 antibody
    • B cell membrane protein antibody
    • B lymphocyte activation marker BLAST 1 antibody
    • B-cell activation marker antibody
    • B-lymphocyte activation marker BLAST-1 antibody
    • BCM 1 surface antigen antibody
    • BCM1 antibody
    • BCM1 surface antigen antibody
    • BLAST 1 antibody
    • BLAST antibody
    • BLAST1 antibody
    • CD 48 antibody
    • CD48 antibody
    • CD48 antigen (B cell membrane protein) antibody
    • CD48 antigen antibody
    • CD48 molecule antibody
    • CD48 protein antibody
    • CD48_HUMAN antibody
    • hCD48 antibody
    • Leucocyte antigen MEM 102 antibody
    • Leukocyte antigen MEM-102 antibody
    • mCD48 antibody
    • MEM 102 antibody
    • MEM-102 antibody
    • MEM102 antibody
    • Signaling lymphocytic activation molecule 2 antibody
    • SLAM family member 2 antibody
    • SLAMF 2 antibody
    • SLAMF2 antibody
    • TCT.1 antibody
    see all

画像

  • Immunocytochemistry/ Immunofluorescence analysis of paraformaldehyde fixed Mouse spleen cell labelling CD48 with ab95608 at 1/100 dilution for 10 minutes at 4°C. Nuclei were stained with DAPI.

    See Abreview

  • Staining of C57BL/6 splenocytes with 0.06 µg of Armenian Hamster IgG Isotype Control PE (open histogram) or 0.06 µg of ab95608 (filled histogram). Cells in the lymphocyte gate were used for analysis.

参考文献

ab95608 has not yet been referenced specifically in any publications.

レビューと Q&A

Abcam guarantees this product to work in the species/application used in this Abreview.
Application
Immunocytochemistry/ Immunofluorescence
Sample
Mouse Cell (spleen)
Specification
spleen
Fixative
Paraformaldehyde
Permeabilization
No
Blocking step
Fc-block as blocking agent for 10 minute(s) · Concentration: 1% · Temperature: 4°C
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投稿 May 10 2013

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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