製品の概要

  • 製品名Anti-CD45RC antibody [GL24] (FLMA)
    CD45RC 一次抗体 製品一覧
  • 製品の詳細
    Rat monoclonal [GL24] to CD45RC (FLMA)
  • 標識FLMA. Ex: 493nm, Em: 528nm
  • 特異性ab25661 recognises CD45RC.
  • アプリケーション適用あり: Flow Cyt, IPmore details
  • 種交差性
    交差種: Mouse
  • 免疫原

    The details of the immunogen for this antibody are not available.

  • エピトープab25661 reacts with an exon C dependent epitope of CD45 glycoprotein.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab25661 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Flow Cyt Use 1µg for 106 cells.
IP Use at an assay dependent dilution.

ターゲット情報

  • 関連性The CD45 family of cell surface glycoprotein antigens exist as a set of isoforms. The patterns of monoclonal antibody recognition of the CD45 phenotypes can be restricted (CD45RA, RB and RC), or broader, such as the CD45 T 200 species. The "restricted" subsets of this group arise as a result of translation of alternatively spliced mRNAs from exons A, B and C (exons 4, 5 and 6), where exons 3-15 encode the extracellular domain of the CD45 molecule. The restricted epitopes are differentially expressed on T and B lymphocytes, including functionally distinct T cells. CD45 (LCA) is a transmembrane phosphotyrosine phosphatase expressed on leucocytes. Myeloid cells do not express the RC isoform.
  • 細胞内局在Membrane; Single-pass type I membrane protein. Membrane raft. Note: Colocalized with DPP4 in membrane rafts.
  • 参照データベース
  • 別名
    • B220 antibody
    • CD45 antibody
    • CD45R antibody
    • EC 3.1.3.48 antibody
    • GP180 antibody
    • L-CA antibody
    • LCA antibody
    • Leukocyte common antigen antibody
    • loc antibody
    • Ly-5 antibody
    • LY5 antibody
    • Ly5, homolog of antibody
    • Lymphocyte antigen 5 antibody
    • Lyt-4 antibody
    • Protein tyrosine phosphatase receptor type C antibody
    • PTPRC antibody
    • Receptor-type tyrosine-protein phosphatase C antibody
    • RT7 antibody
    • T200 antibody
    • T200 Glycoprotein antibody
    see all

Anti-CD45RC antibody [GL24] (FLMA) (ab25661) 使用論文

This product has been referenced in:
  • Johnson P  et al. Identification of the alternatively spliced exons of murine CD45 (T200) required for reactivity with B220 and other T200-restricted antibodies. J Exp Med 169:1179-84 (1989). Read more (PubMed: 2466938) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"