Anti-CD45RA 抗体 [MEM-56], prediluted (Allophycocyanin) (ab30507)


  • 製品名Anti-CD45RA antibody [MEM-56], prediluted (Allophycocyanin)
    CD45RA 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [MEM-56] to CD45RA, prediluted (Allophycocyanin)
  • 標識Allophycocyanin. Ex: 645nm, Em: 660nm
  • 特異性ab30507 recognises CD45RA antigen.
  • アプリケーション適用あり: Flow Cytmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Thymocytes and T lymphocytes (Human)

  • 特記事項

    The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use.



Our Abpromise guarantee covers the use of ab30507 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Flow Cyt
  • 追加情報Flow Cyt: Use 20µl for 106 cells or 100 ul of whole blood.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity.
    • 関連疾患Severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive
      Multiple sclerosis
    • 配列類似性Belongs to the protein-tyrosine phosphatase family. Receptor class 1/6 subfamily.
      Contains 2 fibronectin type-III domains.
      Contains 2 tyrosine-protein phosphatase domains.
    • ドメインThe first PTPase domain interacts with SKAP1.
    • 翻訳後修飾Heavily N- and O-glycosylated.
    • 細胞内局在Membrane. Membrane raft. Colocalized with DPP4 in membrane rafts.
    • Information by UniProt
    • 参照データベース
    • 別名
      • B220 antibody
      • CD45 antibody
      • CD45 antigen antibody
      • CD45R antibody
      • EC antibody
      • GP180 antibody
      • L-CA antibody
      • LCA antibody
      • Leukocyte common antigen antibody
      • Loc antibody
      • Ly-5 antibody
      • LY5 antibody
      • Ly5, homolog of antibody
      • Lymphocyte antigen 5 antibody
      • Lyt-4 antibody
      • Protein tyrosine phosphatase, receptor type, C antibody
      • Protein tyrosine phosphatase, receptor type, c polypeptide antibody
      • Ptprc antibody
      • PTPRC_HUMAN antibody
      • Receptor-type tyrosine-protein phosphatase C antibody
      • RT7 antibody
      • T200 antibody
      • T200 glycoprotein antibody
      • T200 leukocyte common antigen antibody
      see all

    Anti-CD45RA antibody [MEM-56], prediluted (Allophycocyanin) (ab30507) 使用論文

    This product has been referenced in:
    • Simmons R  et al. High frequency, sustained T cell responses to PARV4 suggest viral persistence in vivo. J Infect Dis 203:1378-87 (2011). Flow Cyt ; Human . Read more (PubMed: 21502079) »
    • Di Mitri D  et al. Reversible senescence in human CD4+CD45RA+CD27- memory T cells. J Immunol 187:2093-100 (2011). Flow Cyt ; Human . Read more (PubMed: 21788446) »

    See all 3 Publications for this product

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