Anti-CD45RA 抗体 [4KB5] (ab755)


  • 製品名Anti-CD45RA antibody [4KB5]
    CD45RA 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [4KB5] to CD45RA
  • アプリケーション適用あり: IHC-P, IHC-Frmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Human hairy cell leukaemia cells.

  • ポジティブ・コントロール
    • Tonsil.



Our Abpromise guarantee covers the use of ab755 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
  • 追加情報Immunohistochemistry: 1 / 10 - 1 / 25 for 30 - 60 mins (ABC method).
    Not tested in other applications.

    Optimal dilutions / concentrations should be determined by the end user.

    This antibody is not suitable for Zenker's fixed tissue sections.
  • ターゲット情報

    • 機能Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity.
    • 関連疾患Severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive
      Multiple sclerosis
    • 配列類似性Belongs to the protein-tyrosine phosphatase family. Receptor class 1/6 subfamily.
      Contains 2 fibronectin type-III domains.
      Contains 2 tyrosine-protein phosphatase domains.
    • ドメインThe first PTPase domain interacts with SKAP1.
    • 翻訳後修飾Heavily N- and O-glycosylated.
    • 細胞内局在Membrane. Membrane raft. Colocalized with DPP4 in membrane rafts.
    • Information by UniProt
    • 参照データベース
    • 別名
      • B220 antibody
      • CD45 antibody
      • CD45 antigen antibody
      • CD45R antibody
      • EC antibody
      • GP180 antibody
      • L-CA antibody
      • LCA antibody
      • Leukocyte common antigen antibody
      • Loc antibody
      • Ly-5 antibody
      • LY5 antibody
      • Ly5, homolog of antibody
      • Lymphocyte antigen 5 antibody
      • Lyt-4 antibody
      • Protein tyrosine phosphatase, receptor type C antibody
      • Protein tyrosine phosphatase, receptor type, C antibody
      • Protein tyrosine phosphatase, receptor type, c polypeptide antibody
      • Ptprc antibody
      • PTPRC_HUMAN antibody
      • Receptor-type tyrosine-protein phosphatase C antibody
      • RT7 antibody
      • T200 antibody
      • T200 glycoprotein antibody
      • T200 leukocyte common antigen antibody
      see all

    Anti-CD45RA antibody [4KB5] 画像

    • ab755 staining human tonsil by IHC-P.

    • ab755 staining CD45RA in formalin-fixed, paraffin-embedded Human tonsil tissue by Immunohistochemistry. Staining was detected using DAB.

    Anti-CD45RA antibody [4KB5] (ab755) 使用論文

    ab755 has not yet been referenced specifically in any publications.

    Product Wall

    The concentration of the current lot of ab8260 that we have in stock is 2.0 mg/ml. However, they also informed me that this concentration does vary from lot to lot. Additionally, they have also let me know that the way the concentration was determined ...

    Read More

    Thank you for your enquiry. Ab755 has been tested for application in Immunohistochemistry, both formalin-fixed paraffin-embedded sections and frozen sections. It is recommended to use this antibody at a dilution of 1:10 - 1:25 in an ABC method and an i...

    Read More