Anti-CD45.1 抗体 [NDS 58] (FITC) (ab33925)

製品の概要

  • 製品名Anti-CD45.1 antibody [NDS 58] (FITC)
    CD45.1 一次抗体 製品一覧
  • 製品の詳細
    Rat monoclonal [NDS 58] to CD45.1 (FITC)
  • 標識FITC. Ex: 493nm, Em: 528nm
  • 特異性MCA415F recognises rat CD45.1 (RT7.1), expressed by rat strains including AO, BN, DA, LEW and PVG. The antibody does not react with the RT7.2 alloantigen.
  • アプリケーション適用あり: Flow Cytmore details
  • 種交差性
    交差種: Rat
  • 免疫原

    Thymocytes from LEW rat.

  • ポジティブ・コントロール
    • Spleen cells

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab33925 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Flow Cyt
  • 追加情報Flow Cyt: Neat - 1/5.
    Use 10µl of the suggested working dilution to label 106 cells in 100µl.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 関連性CD45 is an essential regulator of leukocyte activation and development, and is now known to be a protein tyrosine phosphatase, e.g. CD45 is able to dephosphorylate the Src family of protein kinases. This activity is now known to be required for signal transduction induced by T and B cell antigen receptor engagement, cytokine signaling and Fc receptor stimulation. The functional state of CD45 also has a pronounced effect on lymphocyte development. CD45 exists in multiple forms, such as the restricted variants and as allelic forms CD45.1/Ly5.1 and CD45.2/Ly5.2. The former arises as a result of alternative splicing of different exons. The specificity of antibodies to CD45.1 and CD45.2 has been exploited in studies in which resolution of donor and recipient cells is essential, such as in gene therapy or bone marrow transplantation.
    • 細胞内局在Type I membrane protein.
    • 参照データベース
    • 別名
      • B220 antibody
      • CD45 antibody
      • CD45 antigen antibody
      • CD45R antibody
      • GP180 antibody
      • L-CA antibody
      • LCA antibody
      • LY5 antibody
      • Protein tyrosine phosphatase receptor type C antibody
      • Protein tyrosine phosphatase, receptor type, c polypeptide antibody
      • Receptor type tyrosine protein phosphatase C antibody
      • T200 antibody
      • T200 glycoprotein antibody
      • T200 leukocyte common antigen antibody
      see all

    Anti-CD45.1 antibody [NDS 58] (FITC) 画像

    • Staining of rat spleen cells with rat anti-rat CD45.1 (FITC) antibody (ab33925).

    Anti-CD45.1 antibody [NDS 58] (FITC) (ab33925) 使用論文

    ab33925 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"