Anti-CD43 抗体 [MEM-59] - Low endotoxin, Azide free (ab46702)

製品の概要

  • 製品名Anti-CD43 antibody [MEM-59] - Low endotoxin, Azide free
    CD43 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [MEM-59] to CD43 - Low endotoxin, Azide free
  • 特異性The antibody MEM-59 recognizes neuraminidase-sensitive epitope on CD43. The antibody activates T lymphocytes and also induces apoptosis in hemopoietic progenitor cells.
  • アプリケーション適用あり: IHC-P, Flow Cyt, IP, WB, Functional Studiesmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Human T lymphocytes

  • ポジティブ・コントロール
    • Positive tissue: spleen, thymus, tonsil
  • 特記事項Preserved by filter sterilization

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab46702 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P Use a concentration of 10 µg/ml.
Flow Cyt Use a concentration of 1 µg/ml. ab170190-Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
IP Use at an assay dependent concentration.
WB Use at an assay dependent concentration. Predicted molecular weight: 40 kDa.
Functional Studies Use at an assay dependent concentration. The antibody activates T lymphocytes and also induces apoptosis in hemopoietic progenitor cells.

ターゲット情報

  • 機能One of the major glycoproteins of thymocytes and T lymphocytes. Plays a role in the physicochemical properties of the T-cell surface and in lectin binding. Presents carbohydrate ligands to selectins. Has an extended rodlike structure that could protrude above the glycocalyx of the cell and allow multiple glycan chains to be accessible for binding. Is a counter receptor for SN/Siglec-1 (By similarity). During T-cell activation is actively removed from the T-cell-APC (antigen-presenting cell) contact site thus suggesting a negative regulatory role in adaptive immune response.
  • 組織特異性Cell surface of thymocytes, T-lymphocytes, neutrophils, plasma cells and myelomas.
  • 翻訳後修飾Glycosylated; has a high content of sialic acid and O-linked carbohydrate structures.
  • 細胞内局在Membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CD 43 antibody
    • CD43 antibody
    • CD43 antigen antibody
    • Galactoglycoprotein antibody
    • GALGP antibody
    • GPL 115 antibody
    • GPL115 antibody
    • Human gene for sialophorin antibody
    • Leucocyte sialoglycoprotein antibody
    • LEUK_HUMAN antibody
    • Leukocyte large sialoglycoprotein antibody
    • Leukocyte sialoglycoprotein antibody
    • Leukosialin antibody
    • LSN antibody
    • Ly-48 antibody
    • sialophorin (gpL115, leukosialin, CD43) antibody
    • Sialophorin antibody
    • Spn antibody
    see all

Anti-CD43 antibody [MEM-59] - Low endotoxin, Azide free (ab46702) 使用論文

ab46702 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"