製品の概要

  • 製品名Anti-CD43 antibody [MEM-59] (Biotin)
    CD43 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [MEM-59] to CD43 (Biotin)
  • 標識Biotin
  • 特異性The antibody recognizes neuraminidase sensitive epitope on CD43 antigen (Leukosialin), which is involved in lymphocyte activation.
  • アプリケーション適用あり: Flow Cyt, IP, WB, IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Tissue/ cell preparation: T lymphocytes (Human).

  • 特記事項

    The purified antibody is conjugated with Biotin-LC-NHS under optimum conditions. The reagent is free of unconjugated biotin.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab28104 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Flow Cyt 1/200. ab18434-Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
IP Use at an assay dependent concentration.
WB Use at an assay dependent concentration.
IHC-P Use at an assay dependent concentration.

ターゲット情報

  • 機能One of the major glycoproteins of thymocytes and T lymphocytes. Plays a role in the physicochemical properties of the T-cell surface and in lectin binding. Presents carbohydrate ligands to selectins. Has an extended rodlike structure that could protrude above the glycocalyx of the cell and allow multiple glycan chains to be accessible for binding. Is a counter receptor for SN/Siglec-1 (By similarity). During T-cell activation is actively removed from the T-cell-APC (antigen-presenting cell) contact site thus suggesting a negative regulatory role in adaptive immune response.
  • 組織特異性Cell surface of thymocytes, T-lymphocytes, neutrophils, plasma cells and myelomas.
  • 翻訳後修飾Glycosylated; has a high content of sialic acid and O-linked carbohydrate structures.
  • 細胞内局在Membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CD 43 antibody
    • CD43 antibody
    • CD43 antigen antibody
    • Galactoglycoprotein antibody
    • GALGP antibody
    • GPL 115 antibody
    • GPL115 antibody
    • Human gene for sialophorin antibody
    • Leucocyte sialoglycoprotein antibody
    • LEUK_HUMAN antibody
    • Leukocyte large sialoglycoprotein antibody
    • Leukocyte sialoglycoprotein antibody
    • Leukosialin antibody
    • LSN antibody
    • Ly-48 antibody
    • sialophorin (gpL115, leukosialin, CD43) antibody
    • Sialophorin antibody
    • Spn antibody
    see all

Anti-CD43 antibody [MEM-59] (Biotin) (ab28104) 使用論文

This product has been referenced in:
  • Alvarado M  et al. MEM-59 monoclonal antibody detects a CD43 epitope involved in lymphocyte activation. Eur J Immunol 25:1051-5 (1995). Read more (PubMed: 7537669) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"