製品の概要

  • 製品名
  • 製品の詳細
    Goat polyclonal to CD40
  • アプリケーション
    適用あり: ELISA, WBmore details
  • 種交差性
    交差種: Mouse
    交差が予測される動物種: Human
  • 免疫原

    Recombinant extracellular domain (Mouse), expressed in mouse NSO cells.

  • 特記事項
    Endotoxin level is <10 ng per mg antibody as determined by the LAL method. This antibody is not recommended for B cell activation.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab10959 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA
WB
  • 追加情報
    ELISA: Use at a concentration of 0.5 - 1 µg/ml. This concentration detects a limit of ~1 ng/well of recombinant mouse CD40.
    WB: Use at a concentration of 0.1 - 0.2 µg/ml. This concentration detects 0.5 ng/lane and 5 ng/lane under non-reducing and reducing conditions, respectively. Detects a band of approximately 48-50 kDa.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能
      Receptor for TNFSF5/CD40LG.
    • 組織特異性
      B-cells and in primary carcinomas.
    • 関連疾患
      Defects in CD40 are the cause of hyper-IgM immunodeficiency syndrome type 3 (HIGM3) [MIM:606843]; also known as hyper-IgM syndrome 3. HIGM3 is an autosomal recessive disorder which includes an inability of B cells to undergo isotype switching, one of the final differentiation steps in the humoral immune system, an inability to mount an antibody-specific immune response, and a lack of germinal center formation.
    • 配列類似性
      Contains 4 TNFR-Cys repeats.
    • 細胞内局在
      Secreted and Cell membrane.
    • Information by UniProt
    • 参照データベース
    • 別名
      • AI326936 antibody
      • B cell associated molecule CD40 antibody
      • B cell surface antigen CD40 antibody
      • B cell-associated molecule antibody
      • B-cell surface antigen CD40 antibody
      • Bp50 antibody
      • CD 40 antibody
      • CD40 antibody
      • CD40 antigen (TNF receptor superfamily member 5) antibody
      • CD40 antigen antibody
      • CD40 molecule antibody
      • CD40 molecule, TNF receptor superfamily member 5 antibody
      • CD40 protein antibody
      • CD40 type II isoform antibody
      • CD40L receptor antibody
      • CDw40 antibody
      • GP39 antibody
      • HIGM1 antibody
      • IGM antibody
      • IMD3 antibody
      • MGC9013 antibody
      • Nerve growth factor receptor related B lymphocyte activation molecule antibody
      • OTTHUMP00000031699 antibody
      • OTTHUMP00000031700 antibody
      • p50 antibody
      • T-BAM antibody
      • TBAM antibody
      • TNF receptor superfamily member 5 antibody
      • TNFRSF5 antibody
      • TNR5_HUMAN antibody
      • TRAP antibody
      • Tumor necrosis factor receptor superfamily , member 5 antibody
      • Tumor necrosis factor receptor superfamily member 5 antibody
      • Tumor necrosis factor receptor superfamily member 5 precursor antibody
      • Tumor necrosis factor receptor superfamily, member 5, isoform CRA_a antibody
      see all

    プロトコール

    参考文献

    ab10959 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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