PE/Cy5® Anti-CD40 抗体 [1C10] (ab25044)
Key features and details
- PE/Cy5® Rat monoclonal [1C10] to CD40
- Suitable for: IP, Flow Cyt, Functional Studies
- Reacts with: Mouse
- Conjugation: PE/Cy5®. Ex: 496nm, Em: 670nm
- Isotype: IgG2a
Related conjugates and formulations
製品の概要
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製品名
PE/Cy5® Anti-CD40 antibody [1C10]
CD40 一次抗体 製品一覧 -
製品の詳細
PE/Cy5® Rat monoclonal [1C10] to CD40 -
由来種
Rat -
標識
PE/Cy5®. Ex: 496nm, Em: 670nm -
アプリケーション
適用あり: IP, Flow Cyt, Functional Studiesmore details -
種交差性
交差種: Mouse -
免疫原
Recombinant fragment corresponding to CD40. sCD40
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特記事項
This antibody closely resembles the gp39/CD40 ligand in its ability to stimulate proliferation of small, resting B lymphocytes in the absence of other cofactors.
This product or portions thereof is manufactured under license from Carnegie Mellon University under U.S. Patent Number 5, 268, 486 and related patents. Cy® and CyDye® are trademarks of Cytiva.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C. Store In the Dark. -
バッファー
pH: 7.1
Preservative: 0.09% Sodium azide
Constituents: PBS, 0.2% Gelatin, 16% Sucrose
Stabilising agent. -
Concentration information loading...
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精製度
Affinity purified -
一次抗体 備考
This antibody closely resembles the gp39/CD40 ligand in its ability to stimulate proliferation of small, resting B lymphocytes in the absence of other cofactors. -
ポリ/モノ
モノクローナル -
クローン名
1C10 -
アイソタイプ
IgG2a -
軽鎖の種類
kappa -
研究分野
関連製品
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Alternative Versions
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab25044の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
IP |
Use at an assay dependent concentration.
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Flow Cyt |
Use at an assay dependent concentration.
|
|
Functional Studies |
Use at an assay dependent concentration.
In vitro induction of proliferation of mature B lymphocytes. |
特記事項 |
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IP
Use at an assay dependent concentration. |
Flow Cyt
Use at an assay dependent concentration. |
Functional Studies
Use at an assay dependent concentration. In vitro induction of proliferation of mature B lymphocytes. |
ターゲット情報
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機能
Receptor for TNFSF5/CD40LG. -
組織特異性
B-cells and in primary carcinomas. -
関連疾患
Defects in CD40 are the cause of hyper-IgM immunodeficiency syndrome type 3 (HIGM3) [MIM:606843]; also known as hyper-IgM syndrome 3. HIGM3 is an autosomal recessive disorder which includes an inability of B cells to undergo isotype switching, one of the final differentiation steps in the humoral immune system, an inability to mount an antibody-specific immune response, and a lack of germinal center formation. -
配列類似性
Contains 4 TNFR-Cys repeats. -
細胞内局在
Secreted and Cell membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 21939 Mouse
- SwissProt: P27512 Mouse
- Unigene: 271833 Mouse
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別名
- AI326936 antibody
- B cell associated molecule CD40 antibody
- B cell surface antigen CD40 antibody
see all
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (1)
ab25044 は 1 報の論文で使用されています。
- Melo-Baez B et al. MicroRNAs from Extracellular Vesicles Secreted by Bovine Embryos as Early Biomarkers of Developmental Competence. Int J Mol Sci 21:N/A (2020). PubMed: 33255183