Anti-CD40 抗体 [1C10] (Allophycocyanin) (ab25567)

製品の概要

• 製品名Anti-CD40 antibody [1C10] (Allophycocyanin)
  CD40 一次抗体 製品一覧
• 製品の詳細
  Rat monoclonal [1C10] to CD40 (Allophycocyanin)
• 標識Allophycocyanin. Ex: 645nm, Em: 660nm
• アプリケーション適用あり: Flow Cyt, IPmore details
• 種交差性
  交差種: Mouse
  
• 免疫原

  The details of the immunogen for this antibody are not available.

• 特記事項

  
  

  This agonistic antibody closely resembles the gp39/CD40 ligand in it's ability to stimulate the proliferation of small, resting B lymphocytes in the absence of other cofactors. This antibody has been shown to be useful in studies of the 'in vitro' induction of proliferation of mature B lymphocytes.

製品の特性

• 製品の状態Liquid
• 保存方法Shipped at 4°C. Store at +4°C.
• バッファーPreservative: 0.09% Sodium Azide
  Constituents: 16% Sucrose, PBS and stabilizing agent.
• Concentration information loading...
• 精製度IgG fraction
• 一次抗体 備考This agonistic antibody closely resembles the gp39/CD40 ligand in it's ability to stimulate the proliferation of small, resting B lymphocytes in the absence of other cofactors. This antibody has been shown to be useful in studies of the 'in vitro' induction of proliferation of mature B lymphocytes.
• ポリ/モノモノクローナル
• クローン名1C10
• アイソタイプIgG2a
• 軽鎖の種類kappa
• 研究分野
  • Immunology
  • Adaptive Immunity
  • B Cells
  • CD

  • Cardiovascular
  • Atherosclerosis
  • Vascular Inflammation
  • Innate and adaptive immunity

  • Stem Cells
  • Hematopoietic Progenitors
  • Lymphoid
  • B Lymphocytic Lineage

  • Stem Cells
  • Hematopoietic Progenitors
  • Myeloid
  • Dendritic Cell Lineage

関連製品

• Compatible Secondaries
  • Goat Anti-Rat IgG H&L (Alexa Fluor® 488) (ab150157)
  • Goat Anti-Rat IgG H&L (HRP) (ab205720)

アプリケーション

ターゲット情報

• 機能Receptor for TNFSF5/CD40LG.
• 組織特異性B-cells and in primary carcinomas.
• 関連疾患Defects in CD40 are the cause of hyper-IgM immunodeficiency syndrome type 3 (HIGM3) [MIM:606843]; also known as hyper-IgM syndrome 3. HIGM3 is an autosomal recessive disorder which includes an inability of B cells to undergo isotype switching, one of the final differentiation steps in the humoral immune system, an inability to mount an antibody-specific immune response, and a lack of germinal center formation.
• 配列類似性Contains 4 TNFR-Cys repeats.
• 細胞内局在Secreted and Cell membrane.

• Target information above from: UniProt accession P25942 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• 参照データベース
  • Entrez Gene: 21939 Mouse
  • SwissProt: P27512 Mouse
  • Unigene: 271833 Mouse
• 別名
  • AI326936 antibody
  • B cell associated molecule CD40 antibody
  • B cell surface antigen CD40 antibody

  • B cell-associated molecule antibody
  • B-cell surface antigen CD40 antibody
  • Bp50 antibody
  • CD 40 antibody
  • CD40 antibody
  • CD40 antigen (TNF receptor superfamily member 5) antibody
  • CD40 antigen antibody
  • CD40 molecule antibody
  • CD40 molecule, TNF receptor superfamily member 5 antibody
  • CD40 protein antibody
  • CD40 type II isoform antibody
  • CD40L receptor antibody
  • CDw40 antibody
  • GP39 antibody
  • HIGM1 antibody
  • IGM antibody
  • IMD3 antibody
  • MGC9013 antibody
  • Nerve growth factor receptor related B lymphocyte activation molecule antibody
  • OTTHUMP00000031699 antibody
  • OTTHUMP00000031700 antibody
  • p50 antibody
  • T-BAM antibody
  • TBAM antibody
  • TNF receptor superfamily member 5 antibody
  • TNFRSF5 antibody
  • TNR5_HUMAN antibody
  • TRAP antibody
  • Tumor necrosis factor receptor superfamily , member 5 antibody
  • Tumor necrosis factor receptor superfamily member 5 antibody
  • Tumor necrosis factor receptor superfamily member 5 precursor antibody
  • Tumor necrosis factor receptor superfamily, member 5, isoform CRA_a antibody

  see all