Anti-CD4 抗体, prediluted (ab75682)

製品の概要

• 製品名Anti-CD4 antibody, prediluted
  CD4 一次抗体 製品一覧
• 製品の詳細
  Rabbit polyclonal to CD4, prediluted
• アプリケーション適用あり: IHC-Pmore details
• 種交差性
  交差種: Human
  
• 免疫原

  Synthetic peptide corresponding to an internal region of human CD4

• ポジティブ･コントロール
  • Human tonsil.

製品の特性

• 製品の状態Prediluted
• 保存方法Shipped at 4°C. Store at +4°C.
• バッファーPreservative: 0.1% Sodium Azide
  Constituents: 1% BSA, 50mM Tris, pH 7.6
• Concentration information loading...
• 精製度Protein A purified
• ポリ/モノポリクローナル
• アイソタイプIgG
• 研究分野
  • Immunology
  • Adaptive Immunity
  • T Cells
  • CD

  • Stem Cells
  • Hematopoietic Progenitors
  • Lymphoid
  • T Lymphocytic Lineage

  • Stem Cells
  • Hematopoietic Progenitors
  • Myeloid
  • Dendritic Cell Lineage

  • Stem Cells
  • Hematopoietic Progenitors
  • Myeloid
  • Monocytic Lineage

  • Immunology
  • Adaptive Immunity
  • Regulatory T Cells

  • Immunology
  • Immune System Diseases
  • Antiviral Signaling
  • HIV-related

関連製品

• Compatible Secondaries
  • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
  • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)

アプリケーション

ターゲット情報

• 機能Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation. Induces the aggregation of lipid rafts.
• 配列類似性Contains 3 Ig-like C2-type (immunoglobulin-like) domains.
  Contains 1 Ig-like V-type (immunoglobulin-like) domain.
• 翻訳後修飾Palmitoylation and association with LCK contribute to the enrichment of CD4 in lipid rafts.
• 細胞内局在Cell membrane. Localizes to lipid rafts. Removed from plasma membrane by HIV-1 Nef protein that increases clathrin-dependent endocytosis of this antigen to target it to lysosomal degradation. Cell surface expression is also down-modulated by HIV-1 Envelope polyprotein gp160 that interacts with, and sequesters CD4 in the endoplasmic reticulum.

• Target information above from: UniProt accession P01730 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• 参照データベース
  • Entrez Gene: 920 Human
  • Omim: 186940 Human
  • SwissProt: P01730 Human
  • Unigene: 631659 Human
• 別名
  • CD 4 antibody
  • CD4 (L3T4) antibody
  • CD4 antibody

  • CD4 antigen (p55) antibody
  • CD4 antigen antibody
  • CD4 molecule antibody
  • CD4 receptor antibody
  • CD4+ Lymphocyte deficiency, included antibody
  • CD4_HUMAN antibody
  • CD4mut antibody
  • L3T4 antibody
  • Leu3 antibody
  • Ly-4 antibody
  • Lymphocyte antigen CD4 antibody
  • MGC165891 antibody
  • OTTHUMP00000238897 antibody
  • p55 antibody
  • T cell antigen T4 antibody
  • T cell antigen T4/LEU3 antibody
  • T cell differentiation antigen L3T4 antibody
  • T cell OKT4 deficiency, included antibody
  • T cell surface antigen T4/Leu 3 antibody
  • T cell surface antigen T4/Leu3 antibody
  • T cell surface glycoprotein CD4 antibody
  • T-cell surface antigen T4/Leu-3 antibody
  • T-cell surface glycoprotein CD4 antibody
  • W3/25 antibody
  • W3/25 antigen antibody

  see all