Anti-CD4 抗体 [EDU-2] (Phycoerythrin) (ab1155)


  • 製品名Anti-CD4 antibody [EDU-2] (Phycoerythrin)
    CD4 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [EDU-2] to CD4 (Phycoerythrin)
  • 標識Phycoerythrin. Ex: 488nm, Em: 575nm
  • アプリケーション適用あり: Flow Cytmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Human T-lymphocytes.



Our Abpromise guarantee covers the use of ab1155 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Flow Cyt
  • 追加情報1. Counting and identification of the T-helper/inducer lymphocyte subset in human lysed whole peripheral blood or mononuclear cells separated by density gradient.
    2. Studies of HIV infection. Patients infected with HIV lose CD4+ and contemporarilyincrease CD8+ lymphocyte subset
    3. Characterization of subtypes of T-cell leukaemias and lymphomas.

    CD4 (PE) immunofluorescence analysis can be performed on a flow cytometerequipped with an excitation source of 488nm and fitted with logarithmic amplifiers.

    10µl ofCD4 (PE) is sufficient for labelling of 1x106 cells.
    Molecular F/P ratio: 1.0
  • ターゲット情報

    • 機能Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation. Induces the aggregation of lipid rafts.
    • 配列類似性Contains 3 Ig-like C2-type (immunoglobulin-like) domains.
      Contains 1 Ig-like V-type (immunoglobulin-like) domain.
    • 翻訳後修飾Palmitoylation and association with LCK contribute to the enrichment of CD4 in lipid rafts.
    • 細胞内局在Cell membrane. Localizes to lipid rafts. Removed from plasma membrane by HIV-1 Nef protein that increases clathrin-dependent endocytosis of this antigen to target it to lysosomal degradation. Cell surface expression is also down-modulated by HIV-1 Envelope polyprotein gp160 that interacts with, and sequesters CD4 in the endoplasmic reticulum.
    • Information by UniProt
    • 参照データベース
    • 別名
      • CD 4 antibody
      • CD4 (L3T4) antibody
      • CD4 antibody
      • CD4 antigen (p55) antibody
      • CD4 antigen antibody
      • CD4 molecule antibody
      • CD4 receptor antibody
      • CD4+ Lymphocyte deficiency, included antibody
      • CD4_HUMAN antibody
      • CD4mut antibody
      • L3T4 antibody
      • Leu3 antibody
      • Ly-4 antibody
      • Lymphocyte antigen CD4 antibody
      • MGC165891 antibody
      • OTTHUMP00000238897 antibody
      • p55 antibody
      • T cell antigen T4 antibody
      • T cell antigen T4/LEU3 antibody
      • T cell differentiation antigen L3T4 antibody
      • T cell OKT4 deficiency, included antibody
      • T cell surface antigen T4/Leu 3 antibody
      • T cell surface antigen T4/Leu3 antibody
      • T cell surface glycoprotein CD4 antibody
      • T-cell surface antigen T4/Leu-3 antibody
      • T-cell surface glycoprotein CD4 antibody
      • W3/25 antibody
      • W3/25 antigen antibody
      see all

    Anti-CD4 antibody [EDU-2] (Phycoerythrin) (ab1155) 使用論文

    ab1155 has not yet been referenced specifically in any publications.

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    Thank you again for your patience. Regarding ab8361 and ab8476, the epitopes have not yet been determined. If you have any more questions, please contact us again.

    Thank you for your enquiry. For ab1089, we don't have information regarding the epitope at this time. For ab1155, please refer to the following references for more information: 1) Proceeding of the Second International Workshop and Conference on human ...

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