製品の概要

  • 製品名Anti-CD38 antibody [FS02]
    CD38 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [FS02] to CD38
  • 特異性This antibody reacts with a type II membrane glycopeptide with a transmembrane sequence near the NH2-terminus.
  • アプリケーション適用あり: Flow Cytmore details
  • 種交差性
    交差種: Human

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab1260 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Flow Cyt
  • 追加情報HIV Syndromes and other clinical situations characterized by lymphocyte in vivoactivation in human lysed whole peripheral blood or mononuclear cells separated by density gradient.

    CD38 immunofluorescence analysis can be performed on a flow cytometerequipped with an excitation source of 488nm and fitted with logarithmic amplifiers.

    10µl ofCD38 is sufficient for labelling of 1x106 cells.
  • ターゲット情報

    • 機能Synthesizes cyclic ADP-ribose, a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system.
    • 組織特異性Expressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma.
    • 配列類似性Belongs to the ADP-ribosyl cyclase family.
    • 発生段階Preferentially expressed at both early and late stages of the B and T-cell maturation. It is also detected on erythroid and myeloid progenitors in bone marrow, where the level of surface expression was shown to decrease during differentiation of blast-forming unit E to colony-forming unit E.
    • 細胞内局在Membrane.
    • Information by UniProt
    • 参照データベース
    • 製品の状態There are 2 isoforms produced by alternative splicing.
    • 別名
      • Acute lymphoblastic leukemia cells antigen CD38 antibody
      • ADP ribosyl cyclase 1 antibody
      • ADP ribosyl cyclase antibody
      • ADP ribosyl cyclase/cyclic ADP-ribose hydrolase antibody
      • ADP-ribosyl cyclase 1 antibody
      • ADPRC 1 antibody
      • ADPRC1 antibody
      • cADPr hydrolase 1 antibody
      • CD 38 antibody
      • CD38 antibody
      • CD38 antigen (p45) antibody
      • CD38 antigen antibody
      • CD38 molecule antibody
      • Cd38-rs1 antibody
      • CD38_HUMAN antibody
      • CD38H antibody
      • Cyclic ADP ribose hydrolase antibody
      • Cyclic ADP ribose hydrolase 1 antibody
      • Cyclic ADP-ribose hydrolase 1 antibody
      • EC 3.2.2.5 antibody
      • Ecto nicotinamide adenine dinucleotide glycohydrolase antibody
      • I-19 antibody
      • I19 (mouse) antibody
      • Lymphocyte differentiation antigen CD38 antibody
      • NAD(+) nucleosidase antibody
      • NIM-R5 antigen antibody
      • NIMR5 antigen (mouse) antibody
      • OTTHUMP00000158633 antibody
      • OTTHUMP00000217743 antibody
      • p45 antibody
      • T10 antibody
      see all

    Anti-CD38 antibody [FS02] (ab1260) 使用論文

    ab1260 has not yet been referenced specifically in any publications.

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    I can confirm that ab1260 is not the agonistic monoclonal antibody (IB4) stated in the literature and unfortunately, we do not have this product in the catalogue. ab1260 has the clone number FS02 instead of IB4 and we have no information regarding...

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    Thank you for your enquiry.

    Having contacted the originators of these antibodies, we can let you know the following about the immunogens:

    ab2577: Tissue / cell preparation (Human thymocytes in foetus). According to our information...

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    Thank you for your email. Ab1260 has been used in the following two publications, please refer to them for more information regarding this antibody: Morra M et al. CD38 is functionally dependent on the TCR/CD3 complex in human T cells. FASEB J 12:58...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"