PE Anti-CD34 抗体 [MEC 14.7] (ab23830)
Key features and details
- PE Rat monoclonal [MEC 14.7] to CD34
- Suitable for: IHC-P, IP, Flow Cyt
- Reacts with: Mouse
- Conjugation: PE. Ex: 488nm, Em: 575nm
- Isotype: IgG2a
Related conjugates and formulations
製品の概要
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製品名
PE Anti-CD34 antibody [MEC 14.7]
CD34 一次抗体 製品一覧 -
製品の詳細
PE Rat monoclonal [MEC 14.7] to CD34 -
由来種
Rat -
標識
PE. Ex: 488nm, Em: 575nm -
特異性
Recognises the murine CD34 cell surface glycoprotein. Murine CD34 is expressed by haematopoietic progenitor cells in the bone marrow, and also by endothelial cells. -
アプリケーション
適用あり: IHC-P, IP, Flow Cytmore details -
種交差性
交差種: Mouse -
免疫原
Cells transfected with recombinant full length protein (Mouse).
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C. -
バッファー
pH: 7.40
Preservative: 0.09% Sodium azide
Constituents: PBS, 1% BSA -
Concentration information loading...
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精製度
Protein G purified -
ポリ/モノ
モノクローナル -
クローン名
MEC 14.7 -
アイソタイプ
IgG2a -
研究分野
関連製品
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Alternative Versions
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab23830の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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IHC-P |
1/20 - 1/200.
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IP |
Use a concentration of 2 - 10 µg/ml.
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|
Flow Cyt | (1) |
1/25 - 1/50.
Use 10μl of the suggested working dilution to label 106 cells in 100μl |
特記事項 |
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IHC-P
1/20 - 1/200. |
IP
Use a concentration of 2 - 10 µg/ml. |
Flow Cyt
1/25 - 1/50. Use 10μl of the suggested working dilution to label 106 cells in 100μl |
ターゲット情報
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機能
Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins. -
組織特異性
Selectively expressed on hematopoietic progenitor cells and the small vessel endothelium of a variety of tissues. -
配列類似性
Belongs to the CD34 family. -
発生段階
On early hematopoietic progenitor cells. -
翻訳後修飾
Highly glycosylated.
Phosphorylated on serine residues by PKC. -
細胞内局在
Membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 12490 Mouse
- SwissProt: Q64314 Mouse
- Unigene: 29798 Mouse
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別名
- CD34 antibody
- CD34 antigen antibody
- CD34 molecule antibody
see all
データシートおよび資料
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Datasheet download
参考文献 (20)
ab23830 は 20 報の論文で使用されています。
- Vieira JMF et al. Overexpression of mir-135b and mir-210 in mesenchymal stromal cells for the enrichment of extracellular vesicles with angiogenic factors. PLoS One 17:e0272962 (2022). PubMed: 35972944
- Li D et al. Isolation and identification of exosomes from feline plasma, urine and adipose-derived mesenchymal stem cells. BMC Vet Res 17:272 (2021). PubMed: 34384449
- Luo H et al. Manufacturing and banking canine adipose-derived mesenchymal stem cells for veterinary clinical application. BMC Vet Res 17:96 (2021). PubMed: 33648493
- Wei W et al. Bone marrow mesenchymal stem cell exosomes suppress phosphate-induced aortic calcification via SIRT6-HMGB1 deacetylation. Stem Cell Res Ther 12:235 (2021). PubMed: 33849640
- Cooke ME et al. 3D Printed Polyurethane Scaffolds for the Repair of Bone Defects. Front Bioeng Biotechnol 8:557215 (2020). PubMed: 33195122