製品の概要

  • 製品名
    Anti-CD34 antibody [ICH-3] (Biotin)
    CD34 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [ICH-3] to CD34 (Biotin)
  • 標識
    Biotin
  • 特異性
    The antibody recognizes the CD34 antigen, some cross reactions with vascular associated adventitia and some basement membranes.
  • アプリケーション
    適用あり: Flow Cytmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Tissue/ cell preparation containing human CD34 protein.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab34483 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Flow Cyt
  • 追加情報
    Flow Cyt: Use at a maximum of 1 µg of reagent for 106 cells.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能
      Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins.
    • 組織特異性
      Selectively expressed on hematopoietic progenitor cells and the small vessel endothelium of a variety of tissues.
    • 配列類似性
      Belongs to the CD34 family.
    • 発生段階
      On early hematopoietic progenitor cells.
    • 翻訳後修飾
      Highly glycosylated.
      Phosphorylated on serine residues by PKC.
    • 細胞内局在
      Membrane.
    • Information by UniProt
    • 参照データベース
    • 別名
      • CD34 antibody
      • CD34 antigen antibody
      • CD34 molecule antibody
      • CD34_HUMAN antibody
      • Cluster designation 34 antibody
      • Hematopoietic progenitor cell antigen CD34 antibody
      • HPCA1 antibody
      • Mucosialin antibody
      • OTTHUMP00000034733 antibody
      • OTTHUMP00000034734 antibody
      see all

    プロトコール

    参考文献

    This product has been referenced in:
    • Berenson RJ  et al. Antigen CD34+ marrow cells engraft lethally irradiated baboons. J Clin Invest 81:951-5 (1988). Read more (PubMed: 2893812) »
    • Watt SM  et al. Distribution and epitope analysis of the cell membrane glycoprotein (HPCA-1) associated with human hemopoietic progenitor cells. Leukemia 1:417-26 (1987). Read more (PubMed: 2444831) »

    See all 3 Publications for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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