Anti-CD3 zeta 抗体 (ab65118)

製品の概要

• 製品名
  Anti-CD3 zeta antibody
  CD3 zeta 一次抗体 製品一覧
• 製品の詳細
  Rabbit polyclonal to CD3 zeta
• アプリケーション
  適用あり: WB, ELISAmore details
• 種交差性
  交差種: Human
  
• 免疫原

  A KLH conjugated synthetic peptide selected from the N terminal region of human CD3 zeta.

• ポジティブ･コントロール
  • Ramos cell line lysates.

製品の特性

• 製品の状態
  Liquid
• 保存方法
  Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
• バッファー
  Preservative: 0.09% Sodium Azide
  Constituents: PBS
• Concentration information loading...
• 精製度
  Immunogen affinity purified
• 特記事項（精製）
  ab65118 was purified through a protein A column, followed by peptide affinity purification.
• ポリ/モノ
  ポリクローナル
• アイソタイプ
  IgG
• 研究分野
  • Immunology
  • Adaptive Immunity
  • T Cells
  • CD

関連製品

• Compatible Secondaries
  • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
  • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)

アプリケーション

ターゲット情報

• 機能
  Probable role in assembly and expression of the TCR complex as well as signal transduction upon antigen triggering.
• 関連疾患
  Defects in CD247 are the cause of immunodeficiency due to defect in CD3-zeta (CD3ZID) [MIM:610163]. An immunological deficiency characterized by T-cells impaired immune response to alloantigens, tetanus toxoid and mitogens.
• 配列類似性
  Belongs to the CD3Z/FCER1G family.
  Contains 3 ITAM domains.
• ドメイン
  The ITAM domains mediate interaction with SHB.
• 翻訳後修飾
  Phosphorylated on Tyr residues after T-cell receptor triggering.
• 細胞内局在
  Membrane.

• Target information above from: UniProt accession P20963 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• 参照データベース
  • Entrez Gene: 919 Human
  • Omim: 186780 Human
  • SwissProt: P20963 Human
  • Unigene: 156445 Human
• 別名
  • 4930549J05Rik antibody
  • A430104F18Rik antibody
  • AW552088 antibody

  • CD247 antibody
  • CD247 antigen antibody
  • Cd247 molecule antibody
  • Cd3 antibody
  • CD3 antigen, zeta polypeptide, isoform CRA_b antibody
  • CD3 antigen, zeta subunit antibody
  • CD3-eta antibody
  • CD3H antibody
  • CD3Q antibody
  • Cd3z antibody
  • CD3Z antigen zeta polypeptide (TiT3 complex) antibody
  • CD3Z_HUMAN antibody
  • CD3zeta antibody
  • CD3zeta chain antibody
  • MGC140430 antibody
  • T cell receptor T3 zeta chain antibody
  • T cell surface glycoprotein CD3 zeta chain antibody
  • T-cell antigen receptor complex, zeta subunit of CD3 antibody
  • T-cell receptor T3 zeta chain antibody
  • T-cell surface glycoprotein CD3 zeta chain antibody
  • T3z antibody
  • TCR zeta chain antibody
  • TCRk antibody
  • TCRZ antibody
  • TCRzeta antibody

  see all

プロトコール

• Western blot protocols