Anti-CD3 epsilon 抗体 [C363.29B] (Phycoerythrin) (ab25380)

製品の概要

  • 製品名Anti-CD3 epsilon antibody [C363.29B] (Phycoerythrin)
    CD3 epsilon 一次抗体 製品一覧
  • 製品の詳細
    Rat monoclonal [C363.29B] to CD3 epsilon (Phycoerythrin)
  • 標識Phycoerythrin. Ex: 488nm, Em: 575nm
  • 特異性ab25380 recognises CD3 epsilon.
  • アプリケーション適用あり: Flow Cyt, IP, Functional Studies, Cellular Activationmore details
  • 種交差性
    交差種: Mouse
  • 免疫原

    The details of the immunogen for this antibody are not available.

  • エピトープThe monoclonal antibody C363.29B recognizes an epitope on the 25kD epsilon chain of the CD3/TCR complex.
  • 特記事項


    In the presence of Fc receptor-bearing accessory cells, soluble C363.29B can activate primed and naïve T cell in vitro. The monoclonal antibody is cytolytic, easily used for cell surface staining and a good immunoprecipitating antibody.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab25380 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Flow Cyt Use 1µg for 106 cells.
IP Use at an assay dependent concentration.
Functional Studies Use at an assay dependent concentration.

ab25380 can be used for in vitro depletion of CD3 positive cells.

Cellular Activation Use at an assay dependent concentration.

ab25380 can activate primed and naive T cell in vitro (accessory cells must be provided).

ターゲット情報

  • 機能The CD3 complex mediates signal transduction.
  • 配列類似性Contains 1 Ig-like (immunoglobulin-like) domain.
    Contains 1 ITAM domain.
  • 細胞内局在Membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CD3 epsilon antibody
    • CD3e antibody
    • CD3e antigen epsilon polypeptide (TiT3 complex) antibody
    • CD3E antigen epsilon polypeptide antibody
    • CD3E antigen, epsilon subunit antibody
    • CD3e molecule epsilon antibody
    • CD3e molecule, epsilon (CD3 TCR complex) antibody
    • CD3e molecule, epsilon (CD3-TCR complex) antibody
    • CD3E_HUMAN antibody
    • IMD18 antibody
    • T cell antigen receptor complex epsilon subunit of T3 antibody
    • T cell surface antigen T3/Leu 4 epsilon chain antibody
    • T cell surface glycoprotein CD3 epsilon chain antibody
    • T-cell surface antigen T3/Leu-4 epsilon chain antibody
    • T-cell surface glycoprotein CD3 epsilon chain antibody
    • T3E antibody
    • TCRE antibody
    see all

Anti-CD3 epsilon antibody [C363.29B] (Phycoerythrin) 画像

  • BALB/c lymph node cells were double stained with ab25380 and with anti-IL2RB (ab24943) at 1µg/106 cells. Small lymphocytes were gated and analyzed on a flow cytometer.

Anti-CD3 epsilon antibody [C363.29B] (Phycoerythrin) (ab25380) 使用論文

This product has been referenced in:
  • Tarrant TK  et al. G protein-coupled receptor kinase-3-deficient mice exhibit WHIM syndrome features and attenuated inflammatory responses. J Leukoc Biol 94:1243-51 (2013). Mouse . Read more (PubMed: 23935208) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"