製品の概要

  • 製品名Anti-CD3 epsilon antibody [145-2C11] (Biotin)
    CD3 epsilon 一次抗体 製品一覧
  • 製品の詳細
    Armenian Hamster monoclonal [145-2C11] to CD3 epsilon (Biotin)
  • 標識Biotin
  • 特異性ab114039 is specific for a 25 kDa protein component (epsilon-T3) of the antigen specific T cell receptor in several Mouse strains. It reacts with all mature T cells and can both activate and inhibit T cell function.
  • アプリケーション適用あり: Flow Cytmore details
  • 種交差性
    交差種: Mouse
  • 免疫原

    H-2Kb sp

  • ポジティブ・コントロール
    • BALB/c Mouse thymocytes or splenic T Cells
  • 特記事項


    This monoclonal antibody, clone 145-2C11, was specifically designed to trigger T cell activation.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab114039 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Flow Cyt Use 1µg for 106 cells.

ターゲット情報

  • 機能The CD3 complex mediates signal transduction.
  • 配列類似性Contains 1 Ig-like (immunoglobulin-like) domain.
    Contains 1 ITAM domain.
  • 細胞内局在Membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CD3 epsilon antibody
    • CD3e antibody
    • CD3e antigen epsilon polypeptide (TiT3 complex) antibody
    • CD3E antigen epsilon polypeptide antibody
    • CD3E antigen, epsilon subunit antibody
    • CD3e molecule epsilon antibody
    • CD3e molecule, epsilon (CD3 TCR complex) antibody
    • CD3e molecule, epsilon (CD3-TCR complex) antibody
    • CD3E_HUMAN antibody
    • IMD18 antibody
    • T cell antigen receptor complex epsilon subunit of T3 antibody
    • T cell surface antigen T3/Leu 4 epsilon chain antibody
    • T cell surface glycoprotein CD3 epsilon chain antibody
    • T-cell surface antigen T3/Leu-4 epsilon chain antibody
    • T-cell surface glycoprotein CD3 epsilon chain antibody
    • T3E antibody
    • TCRE antibody
    see all

Anti-CD3 epsilon antibody [145-2C11] (Biotin) 画像

  • Flow cytometric analysis of CD3 epsilon in BALB/c thymocyte cells stained with ab114039 at 1 µg per 106 cells.
    Biotin Hamster IgG was used as isotypic control.
    Percentage of cells stained above control: 50.2%.
  • Flow Cytometric analysis of CD3 epsilon in BALB/c splenic T cells stained with ab114039 at 1 µg per 106 cells.
    Biotin Hamster IgG was used as isotypic control.
    Percentage of cells stained above control: 87.6%.

Anti-CD3 epsilon antibody [145-2C11] (Biotin) (ab114039) 使用論文

This product has been referenced in:
  • Hirsch R  et al. Effects of in vivo administration of anti-T3 monoclonal antibody on T cell function in mice. I. Immunosuppression of transplantation responses. J Immunol 140:3766-72 (1988). Read more (PubMed: 3286764) »
  • Leo O  et al. Identification of a monoclonal antibody specific for a murine T3 polypeptide. Proc Natl Acad Sci U S A 84:1374-8 (1987). Read more (PubMed: 2950524) »

See all 2 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"