Anti-CD3 epsilon 抗体 [145-2C11] (ab25468)

製品の概要

  • 製品名Anti-CD3 epsilon antibody [145-2C11]
    CD3 epsilon 一次抗体 製品一覧
  • 製品の詳細
    Armenian Hamster monoclonal [145-2C11] to CD3 epsilon
  • 特異性ab25468 recognises CD3 epsilon.
  • アプリケーション適用あり: Flow Cyt, WB, IP, Celluar Activation, Functional Studiesmore details
  • 種交差性
    交差種: Mouse
  • 免疫原

    Tissue/ cell preparation: H2Kb specific mouse cytotoxic T lymphocyte clone BM10 37.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab25468 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Flow Cyt
WB
IP
Celluar Activation
Functional Studies
  • 追加情報Cellular activation: Use at an assay dependent dilution.
    Note: In the presence of Fc receptor bearing accessory cells, soluble ab25468 can activate primed and naive T cell in vitro. Immobilized ab25468 can activate both normal T lymphocytes and cloned T cell lines. Under certain conditions, T cell activation by ab25468 may result in apoptotic cell death.
    Flow Cyt: Use at an assay dependent dilution.
    FuncS: Use at an assay dependent dilution.
    Note: ab25468 can be used for in vitro depletion of CD3+ cells, for induction of redirected lysis of specific target cells by CTL clones and for blocking lysis of specific target cells by antigen specific CTL's.
    IP: Use at an assay dependent dilution.
    WB: Use at an assay dependent dilution. Predicted molecular weight: 23 kDa.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能The CD3 complex mediates signal transduction.
    • 配列類似性Contains 1 Ig-like (immunoglobulin-like) domain.
      Contains 1 ITAM domain.
    • 細胞内局在Membrane.
    • Information by UniProt
    • 参照データベース
    • 別名
      • CD3 epsilon antibody
      • CD3e antibody
      • CD3e antigen epsilon polypeptide (TiT3 complex) antibody
      • CD3E antigen epsilon polypeptide antibody
      • CD3E antigen, epsilon subunit antibody
      • CD3e molecule epsilon antibody
      • CD3e molecule, epsilon (CD3 TCR complex) antibody
      • CD3e molecule, epsilon (CD3-TCR complex) antibody
      • CD3E_HUMAN antibody
      • IMD18 antibody
      • T cell antigen receptor complex epsilon subunit of T3 antibody
      • T cell surface antigen T3/Leu 4 epsilon chain antibody
      • T cell surface glycoprotein CD3 epsilon chain antibody
      • T-cell surface antigen T3/Leu-4 epsilon chain antibody
      • T-cell surface glycoprotein CD3 epsilon chain antibody
      • T3E antibody
      • TCRE antibody
      see all

    Anti-CD3 epsilon antibody [145-2C11] (ab25468) 使用論文

    ab25468 has not yet been referenced specifically in any publications.

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    Thank you for contacting us.

    The following paper may be helpful in determining the binding affinity of this antibody. Basically, this information can be measured in an indirectELISA assay using the antibody and a purified antigen such as ab11...

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    Thank you for your enquiry. Unfortunately, we are unable to sub-isotype Hamster IgG. We are only able to provide the isotype as being Hamster IgG.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"