製品の概要

  • 製品名
    Anti-CD28 antibody [CD28.2] (PerCP)
    CD28 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [CD28.2] to CD28 (PerCP)
  • 標識
    PerCP. Ex: 482nm, Em: 675nm
  • 特異性
    Reacts with CD28, a disulfide-linked homodimeric type I glycoprotein (monomer of Mw 44 kDa) which is a critical costimulatory receptor of T cells.
  • アプリケーション
    適用あり: Flow Cytmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Non human primates
  • 免疫原

    DC28.1.3.3 hybridoma cells

  • ポジティブ・コントロール
    • Human blood cells
  • 特記事項

    The purified antibody (>95% by SDS-PAGE) is conjugated with Peridinin-chlorophyll-protein complex (PerCP) under optimum conditions.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab88034 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Flow Cyt Use 10µl for 106 cells. ab118658-Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.

ターゲット情報

  • 機能
    Involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival.
  • 組織特異性
    Expressed in T-cells and plasma cells, but not in less mature B-cells.
  • 配列類似性
    Contains 1 Ig-like V-type (immunoglobulin-like) domain.
  • 細胞内局在
    Membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CD 28 antibody
    • CD28 antibody
    • CD28 antigen antibody
    • CD28 molecule antibody
    • CD28_HUMAN antibody
    • MGC138290 antibody
    • T cell antigen CD28 antibody
    • T cell specific surface glycoprotein antibody
    • T cell specific surface glycoprotein CD28 antibody
    • T-cell-specific surface glycoprotein CD28 antibody
    • TP44 antibody
    see all

プロトコール

参考文献

This product has been referenced in:
  • Scharschmidt E  et al. Degradation of Bcl10 induced by T-cell activation negatively regulates NF-kappa B signaling. Mol Cell Biol 24:3860-73 (2004). Read more (PubMed: 15082780) »
  • Jeong SH  et al. Immunization with hepatitis C virus-like particles induces humoral and cellular immune responses in nonhuman primates. J Virol 78:6995-7003 (2004). Read more (PubMed: 15194776) »

See all 7 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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