製品の概要

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab89258 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/1000. Predicted molecular weight: 29 kDa.
Neutralising Use at an assay dependent concentration. Soluble TNFRSF7 (also called CD27) attenuates CD27 Ligand-induced proliferation of Human T-cells. In the presence of 2.5 µg/mL of soluble TNFRSF7, 10µg/mL recombinant CD27 ligand, 2.5-10 µg/ml of ab89258 could attenuate proliferation of human T-cells by 50% (3H-thymidine Incorporation).
Flow Cyt 1/50 - 1/100. ab170190-Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.

ターゲット情報

  • 機能
    Receptor for CD70/CD27L. May play a role in survival of activated T-cells. May play a role in apoptosis through association with SIVA1.
  • 組織特異性
    Found in most T-lymphocytes.
  • 配列類似性
    Contains 3 TNFR-Cys repeats.
  • 翻訳後修飾
    Phosphorylated and O-glycosylated.
  • 細胞内局在
    Membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CD 27 antibody
    • CD27 antibody
    • CD27 antigen antibody
    • CD27 molecule antibody
    • CD27_HUMAN antibody
    • CD27L receptor antibody
    • LPFS2 antibody
    • MGC20393 antibody
    • OTTHUMP00000238557 antibody
    • S152 antibody
    • T cell activation antigen CD27 antibody
    • T cell antivation antigen S152 antibody
    • T-cell activation antigen CD27 antibody
    • T14 antibody
    • TNFRSF 7 antibody
    • TNFRSF7 antibody
    • TNFSF7 antibody
    • Tp 55 antibody
    • Tp55 antibody
    • Tumor necrosis factor receptor superfamily member 7 antibody
    see all

画像

  • Anti-CD27 antibody [MM0165-7H21] (ab89258) at 1/1000 dilution (Mouse anti human TNFRSF7) + Human spleen tissues lysate

    Predicted band size : 29 kDa
    Observed band size : 42 kDa (why is the actual band size different from the predicted?)

参考文献

ab89258 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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