製品の概要

  • 製品名Anti-CD20 antibody [B-Ly1]
    CD20 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [B-Ly1] to CD20
  • アプリケーション適用あり: Flow Cyt, Celluar Activation, IPmore details
  • 種交差性
    交差種: Human
  • 免疫原

    The details of the immunogen for this antibody are not available.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab25607 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Flow Cyt Use 1µg for 106 cells. ab170190-Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
Celluar Activation Use at an assay dependent concentration. In vitro activation of B cells.
IP Use at an assay dependent concentration.

ターゲット情報

  • 機能This protein may be involved in the regulation of B-cell activation and proliferation.
  • 組織特異性Expressed on B-cells.
  • 関連疾患Defects in MS4A1 are the cause of immunodeficiency common variable type 5 (CVID5) [MIM:613495]; also called antibody deficiency due to CD20 defect. CVID5 is a primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antigen. The defect results from a failure of B-cell differentiation and impaired secretion of immunoglobulins; the numbers of circulating B cells is usually in the normal range, but can be low.
  • 配列類似性Belongs to the MS4A family.
  • 翻訳後修飾Phosphorylated. Might be functionally regulated by protein kinase(s).
  • 細胞内局在Membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • APY antibody
    • ATOPY antibody
    • B lymphocyte antigen CD20 antibody
    • B Lymphocyte Cell Surface Antigen B1 antibody
    • B-lymphocyte antigen CD20 antibody
    • B-lymphocyte cell-surface antigen B1 antibody
    • B-lymphocyte surface antigen B1 antibody
    • B1 antibody
    • Bp 35 antibody
    • Bp35 antibody
    • CD 20 antibody
    • CD20 antibody
    • CD20 antigen antibody
    • CD20 receptor antibody
    • CD20_HUMAN antibody
    • CVID5 antibody
    • Fc epsilon receptor I beta chain antibody
    • Fc Fragment of IgE high affinity I receptor for beta polypeptide antibody
    • FCER1B antibody
    • High affinity immunoglobulin epsilon receptor subunit beta antibody
    • IgE Fc receptor subunit beta antibody
    • IGEL antibody
    • IGER antibody
    • IGHER antibody
    • LEU 16 antibody
    • LEU16 antibody
    • leukocyte surface antigen Leu 16 antibody
    • Leukocyte surface antigen Leu-16 antibody
    • Ly44 antibody
    • Membrane spanning 4 domains A1 antibody
    • Membrane spanning 4 domains subfamily A member 2 antibody
    • Membrane-spanning 4-domains subfamily A member 1 antibody
    • MS4A1 antibody
    • MS4A2 antibody
    • S7 antibody
    see all

Anti-CD20 antibody [B-Ly1] (ab25607) 使用論文

This product has been referenced in:
  • Kotani N  et al. Fibroblast Growth Factor Receptor 3 (FGFR3) Associated with the CD20 Antigen Regulates the Rituximab-induced Proliferation Inhibition in B-cell Lymphoma Cells. J Biol Chem 287:37109-18 (2012). Read more (PubMed: 22932894) »
  • Nozaki K & Pestronk A High aldolase with normal creatine kinase in serum predicts a myopathy with perimysial pathology. J Neurol Neurosurg Psychiatry 80:904-8 (2009). Human . Read more (PubMed: 19240048) »

See all 3 Publications for this product

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Unfortunately we have not performed any kind of cytotoxicity assays with these antibodies. I was however able to find a paper referring to these assays with a murine monoclonal antibody anti CD20 from clone [B-Ly1...

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Thank you for your enquiry. I can confirm that Sodium Azide is not added in this product. Also, no preservatives or amine-containing buffer salts added.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"