Anti-CD20 抗体 [AT80] (FITC) (ab27856)

製品の概要

  • 製品名Anti-CD20 antibody [AT80] (FITC)
    CD20 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [AT80] to CD20 (FITC)
  • 標識FITC. Ex: 493nm, Em: 528nm
  • 特異性Recognizes the human CD20 cell surface antigen, a glycoprotein of 35-37kD. Although it has not been epitope mapped, we believe that it recognizes a region on the extracellular surface of CD20 because no permeabilization treatment is required prior to staining.
  • アプリケーション適用あり: Flow Cytmore details
  • 種交差性
    交差種: Human
  • 免疫原

    NS-O cells transfected with human CD20.

  • ポジティブ・コントロール
    • Human peripheral blood cells
  • 特記事項

    Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC).

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab27856 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Flow Cyt
  • 追加情報Flow Cyt: Use 10µl of neat solution or dilute to a maximum of 1/10 to label 106 cells or 100µl whole blood.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能This protein may be involved in the regulation of B-cell activation and proliferation.
    • 組織特異性Expressed on B-cells.
    • 関連疾患Defects in MS4A1 are the cause of immunodeficiency common variable type 5 (CVID5) [MIM:613495]; also called antibody deficiency due to CD20 defect. CVID5 is a primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antigen. The defect results from a failure of B-cell differentiation and impaired secretion of immunoglobulins; the numbers of circulating B cells is usually in the normal range, but can be low.
    • 配列類似性Belongs to the MS4A family.
    • 翻訳後修飾Phosphorylated. Might be functionally regulated by protein kinase(s).
    • 細胞内局在Membrane.
    • Information by UniProt
    • 参照データベース
    • 別名
      • APY antibody
      • ATOPY antibody
      • B lymphocyte antigen CD20 antibody
      • B Lymphocyte Cell Surface Antigen B1 antibody
      • B-lymphocyte antigen CD20 antibody
      • B-lymphocyte cell-surface antigen B1 antibody
      • B-lymphocyte surface antigen B1 antibody
      • B1 antibody
      • Bp 35 antibody
      • Bp35 antibody
      • CD 20 antibody
      • CD20 antibody
      • CD20 antigen antibody
      • CD20 receptor antibody
      • CD20_HUMAN antibody
      • CVID5 antibody
      • Fc epsilon receptor I beta chain antibody
      • Fc Fragment of IgE high affinity I receptor for beta polypeptide antibody
      • FCER1B antibody
      • High affinity immunoglobulin epsilon receptor subunit beta antibody
      • IgE Fc receptor subunit beta antibody
      • IGEL antibody
      • IGER antibody
      • IGHER antibody
      • LEU 16 antibody
      • LEU16 antibody
      • leukocyte surface antigen Leu 16 antibody
      • Leukocyte surface antigen Leu-16 antibody
      • Ly44 antibody
      • Membrane spanning 4 domains A1 antibody
      • Membrane spanning 4 domains subfamily A member 2 antibody
      • Membrane-spanning 4-domains subfamily A member 1 antibody
      • MS4A1 antibody
      • MS4A2 antibody
      • S7 antibody
      see all

    Anti-CD20 antibody [AT80] (FITC) 画像

    Anti-CD20 antibody [AT80] (FITC) (ab27856) 使用論文

    ab27856 has not yet been referenced specifically in any publications.

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    I am sorry about that mix up, I mistyped the abnumber. Thank you for bringing it to my attention.   Again, this type of assay has not been tested by our lab but I have spoken with the lab and can offer you the following advice. That being said, I wo...

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    Thank you for your inquiry about ab27856. I've spoken with the lab about this and received the following response: This product has not been tested for neutralization assays. We have only tested it for use with flow cytometry. I’m guessing you are in...

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    Thank you for your enquiry. Although ab27856 has not been epitope mapped, the originator believes that it recognizes a region on the extracellular surface of CD20 because no permeabilization treatment is required prior to staining. For ab1169, th...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"